• 目的提高三七收率纯度

    ObjectiveTo increase the yield and the purity of total saponin of Panax notoginseng.

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  • 前言:目的:制备三七皂苷分散

    Objective: to prepare for the total sapogenin disperse tablet of Notoginseng.

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  • 目的研究三七(PNS)对神经细胞保护作用

    OBJECTIVE: to study the neuroprotective effects of saponins of Panax notoginseng (PNS).

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  • 这个最佳条件下试验,三七总皂苷提取率为82.41%。

    Under this optimal condition, the extraction rate of total saponins was 82.41%.

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  • 分别建立了三七缓释片重楼分散质量标准

    The quality standard of Panax notoginseng sustained-release tablets and Paris Polyphylla saponin dispersible tablets were different established.

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  • 目的研究三七总皂苷大鼠肝脏低温保存影响及其作用机理

    Objective to investigate the effects and mechanism of Panax Notoginseng saponins on rat liver during cold preservation.

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  • 前言:目的:确立血塞通滴丸(三七)最佳成型工艺

    Objective: to establish the optimum preparation process for Xuesaitong Dropping Pills (total saponin of Radix Notoginseng).

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  • 方法主要成份大黄素、大黄酸、三七总皂苷进行定性鉴别

    METHOD The main components, emodin and rhein and total notogisennoside were qualitatively identified.

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  • 目的了解三七总皂苷抗肝损伤方面药理作用临床进展情况。

    Objective:To know about the pharmacological action and clinical advances in Parax notoginseng for anti-hepatic lesion.

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  • 目的探讨三七总黄芪防治2糖尿病动脉粥样硬化作用机制

    Objective to investigate the role and mechanism of Astragalus (AS) and Panax Notoginseng Saponins (PNS) in treatment of type 2 diabetic atherosclerosis.

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  • 目的:本实验制备了三七皂苷分散达到提高药物溶出,改善吸收

    OBJECTIVE: to prepare Radix Notoginseng total Saponin Dispersible tablets to enhance the dissolution rate and improve its absorbability.

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  • 目的研究三七皂苷(PNGS)大鼠肝脏低温保存影响及其作用机理

    Objective to investigate the effects and mechanism of Panax Notoginseng saponins (PNGS) on rat liver during cold preservation.

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  • 三七总注射剂广泛用于临床其非注射剂型开发应用非常有限

    Panax notoginseng saponin (PNS) injection has been widely used in clinic, but the development and application of non-injectable PNS formulations are still insufficient.

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  • 目的研制三七总皂苷生物黏附考察体外动力学离体肠黏膜的黏附

    OBJECTIVE To prepare the Panax Notoginseng Saponines (PNS) bioadhesive tablets, and to study their release kinetics and bioadhesive tablets force to rabbit small intestine in vitro.

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  • 结论代动力学药效学结果证明三七总皂苷鼻腔给药制剂具有好的开发前景

    Conclusion The results of pharmacokinetics and pharmacodynamics demonstrated that PNS intranasal preparation has a pretty prospect to develop.

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  • 目的研究三七PNS)对静脉内皮细胞HUVEC增殖作用。

    Objective: To investigate the proliferation efficiency of total saponins of Panax notoginseng (PNS) on human umbilical vein endothelial cell (HUVEC).

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  • 目的研究三七总皂苷(PNs)脂质体生理适应性及其对心脑血管保护作用

    AIM: to investigate the physiological compatibility and protective effects on cardio-cerebrovascular diseases of Panax notoginseng (PNS) liposomes in animals.

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  • 目的研究三七总皂苷(PNS)脂质体制备方法其生理适应性进行初步考察。

    AIM: to study the preparation and physiological compatibility of pulmonary administration with Saponius of Panax Notoginseng (PNS) liposomes.

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  • 方法:采用高效液相色谱法测定我们制备三七皂苷分散血栓通制剂的溶出度

    METHODS: The dissolution rates of Radix Notoginseng total Saponin Dispersible tablets and Xueshuantong preparation were determined by HPLC.

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  • 三七皂苷(PNS)三七主要生理活性成分广泛地应用心血管疾病治疗。

    Panax notoginseng saponins (PNS) are the chief active constituents of Panax notoginseng, and have been widely used for the treatment of cardiovascular diseases.

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  • 目的研究复方配伍三七总皂苷PNS胃肠道稳定性渗透性脂溶性的影响

    Objective:To investigate the effects of compound compatibility on the stability in gastrointestinal tract, membrane permeability and lipophilicity of panaxnotoginseng saponins (PNS).

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  • 目的探讨三七皂苷(PNS)急性梗死患者单核细胞CD 14TLR4影响

    Objective It is to discuss the influence of total saponins panax notoginseng (PNS) on CD14 and TLR4 of mononuclear cell in acute cerebral infarct patients.

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  • 方法三七皂苷含量为评价指标,采用正交试验法优选超声波提取三七总皂苷工艺条件。

    Methods the optimal process of extracting total saponins was studied by orthogonal test, as the content of the total saponins being the measurement.

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  • 主要观察指标三七总皂苷对阿尔茨海默病大脑碱能神经元分布胆碱乙酰基转移酶影响

    MAIN OUTCOME MEASURES: Effect of PNS on distribution of cholinergic neuron and ChAT content in cerebral tissue of AD rat models.

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  • 目的观察三七皂苷(PNS)老年性痴呆(AD)模型大脑碱能神经病理损害保护作用

    Objective: to observe the protective effect of Panax notoginseng saponins (PNS) against pathological lesion of cholinergic neuron in rat model with Alzheimer's disease (AD).

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  • 结果三七总皂苷有效降低缺血再灌注损伤脑梗死体积明显减轻脑缺血区脑屏障破坏程度

    Result: PNS could reduce infarct volume of cerebral ischemia-reperfusion injury in rats, reduce the extent of the damage in blood-brain barrier significantly.

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  • 三七乙醇提取后,用d _(101)大孔吸附树脂进行纯化,所得三七总皂苷含量90%以上,杂质较少。

    PNS was extracted with ethanol from Radix notoginseng by infiltrating, and purified with D101 macroporous resin, its content up to 90%.

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  • 方法应用MTT比色法研究三七总皂苷丹参注射液苦参碱体外培养大鼠肝癌细胞CBRH7919影响的量效关系。

    Methods: Different concentrations of PNS, matrine and Danshen injection were used to detect the antineoplastic effects on CBRH7919 cells in vitro by using MTT Method.

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  • 方法检索1994 ~ 2006年国内公开发表医学期刊报道应用三七总皂苷注射剂不良反应案例,对其进行统计分析。

    METHODS: ADR cases induced by SPN injection that retrieved from domestic medical journals between 1994 and 2006 were analyzed statistically.

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  • 方法检索1994 ~ 2006年国内公开发表医学期刊报道应用三七总皂苷注射剂不良反应案例,对其进行统计分析。

    METHODS: ADR cases induced by SPN injection that retrieved from domestic medical journals between 1994 and 2006 were analyzed statistically.

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