采用冻融法制备了丹参酮的脂质体。
Tanshinone liposomes were prepared by freeze thawing (FT) method.
目的评价丹参酮治疗点滴型银屑病的疗效。
ObjectiveTo explore the curative effect of treating psoriasis guttate with tanshinone.
目的:建立妇经冲剂丹参酮a质量控制方法。
OBJECTIVE: To establish a quality control method for Fujin granules.
本发明提供了一种丹参酮固体分散物及其制备方法。
The present invention relates to a tanshinone solid dispersion and its preparation method.
目的探讨丹参酮滴耳液对耳部感染性疾病的治疗效果。
Objective To investigate the effectiveness of tanshinone ear drop in the treatment of infected ear diseases.
目的:测定八味丹参茶中丹参酚酸B和总丹参酮的含量。
Objective:To determine the contents of salvianoic acid B and total tanshiones in Baweidanshen tea.
结论:采用溶剂沉积法提高丹参酮的体外溶出度是可行的。
Conclusion: The dissolution rate of tanshinone in vitro can be improved with solvent deposition method.
目的筛选丹参酮自乳化药物传递系统的处方,考察其稳定性。
Objective To screen the formulation for tanshinone self-emulsifying drug delivery system (SEDDS) and evaluate its stability.
目的:观察丹参酮、纳络酮对缺血再灌注心肌局部血流量的影响。
AIM: To investigate the effects of tanshinone and naloxone on regional myocardial blood flow (RMBF) during ischemia and reperfusion.
方法:用超声-匀浆-冷冻干燥法制备丹参酮IIA纳米脂质体。
METHODS Tanshinone IIA nano-liposomes were prepared by ultrasonic bath-refining lyophilization method.
采用高效液相色谱法对方中丹参所含丹参酮IIA进行含量测定。
The content of Tanshinone IIA in Salvia of Fufangjiangzhi capsule was determined by HPLC.
预测结果:用恒温加速试验线性模预测总丹参酮的有效期为471天。
The expiration dates of totaltanshinones detected by classic isothermal accelerated tests , the result was 471days.
目的探讨丹参酮对大鼠神经细胞脑缺血样损伤模型的保护作用及其机制。
AIM To investigate protective effects and mechanism of tanshinones on ischemia-like injury models.
主要成份:银杏、丹参酮、金银花、杜鹃花、芦荟、氨基酸洁肤因子等。
Ingredient: Ginkgo, Tanshinone, Honeysuckle, Azaleas and Aloes Extract, Amino Acid Cleanser Factor.
大鼠灌胃隐丹参酮和丹参酮提取物后的药-时曲线分别符合一房室和二房室模型。
The plasma concentration-time curves of cryptotanshinone were best fitted with one-compartment and two-compartment models for cryptotanshinone and tanshinones extract of Salvia miltiorrhiza Bge.
结论:复方丹参缓释片中脂溶性成分增溶处理后,冰片、丹参酮的溶解性显著提高。
Conclusion: the liposoluble constituent were been to process by solubilizing, the solubility of borneol and tanshinone were remarkably increased.
分别采用冻融法、逆相蒸发法、超声-匀浆-冷冻干燥法制备丹参酮IIA纳米脂质体。
Methods: TotanshinoneIIA Nano-liposomes were prepared by freeze-melt, reverse phase evaporation and ultrasonic bath-refining-freeze-drying.
结论EH病人病程早期PBMC处于预激活状态,丹参酮能抑制预激活的PBMC进一步激活。
CONCLUSION PBMC are preactivated in patients with EH during early stage of the diseased course. Tanshinone can inhibit further activation of preactivated PBMC.
目的研究丹参酮对原发性高血压(EH)病人病程早期外周血单核细胞(PBMC)激活的作用。
OBJECTIVE To investigate the effects of tanshinone on peripheral blood monocytes (PBMC) activation in patients with essential hypertension (EH) during early stage of the diseased course.
考察了聚乙烯吡咯烷酮(pvp)以及冻融处理对丹参酮脂质体的药物渗漏和微粒聚结特性的影响。
The effects of PVP in formulation and freeze thawing steps on drug leakage and aggregation of tanshinone liposomes were investigated.
结论丹参酮能够在抗心肌肥厚的同时通过减少钙内流、缩短动作电位时间,起到预防心律失常的作用。
ConclusionTanshinone not only reverses the myocardial hypertrophy, but also reduces calcium influx and shorten action potential duration which are beneficial to prevent arrhythmia.
免疫细胞化学染色及ELISA法检测发现,丹参酮IIA作用组肝癌细胞VEGF表达和培养液中VEGF分泌量明显减少,与未加药对照组相比差异有统计学意义(P<0.01)。
The expression of VEGF in Tanshinone IIAtreated group was significantly lower than that in control group (P<0.01). The similar result could be observed in cell culture fluid with ELISA assay.
免疫细胞化学染色及ELISA法检测发现,丹参酮IIA作用组肝癌细胞VEGF表达和培养液中VEGF分泌量明显减少,与未加药对照组相比差异有统计学意义(P<0.01)。
The expression of VEGF in Tanshinone IIAtreated group was significantly lower than that in control group (P<0.01). The similar result could be observed in cell culture fluid with ELISA assay.
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