采用牛肝酯酶拆分紫杉醇侧链合成中生成对映异构体化合物的新方法。
A novel enzymatic resolution of an enantiomeric mixture, from the synthesis of side chain of taxol, using beef liver esterase is described.
介绍抗癌药物紫杉醇的几种合成方法,重点阐述紫杉醇手性侧链合成以及应用紫杉醇手性侧链的重要性。
The methods for synthesizing anticarcinogen taxol are introduced. The synthesis of chiral side chain of taxol and the significance of application of chiral side chain are described in detail.
介绍抗癌药物紫杉醇的几种合成方法,重点阐述紫杉醇手性侧链合成以及应用紫杉醇手性侧链的重要性。
The synthesis of chiral side chain of taxol and the significance of application of chiral side chain are described in detail.
究其原因1)C-13侧链合成不足,2)紫杉醇核心部分与侧链结合处酶—苯丙基转移酶(BAPT)表达量低。
The reason for that were 1) the scarcity of C-13 side chain synthesis, 2) the low expression level of the phenylpropanoyltransferase (BAPT) transfering the side chain directly to baccatinlll.
由于在侧链的合成中,有手性碳原子发生了构型翻转,因此我们合成了一个相应的多利培南光学异构体,以利于质量控制。
Due to the configuration inversions of chiral carbon in the synthesis of side chain, we synthesized the corresponding optical isomer of doripenem for quality control.
我们通过“一锅法”合成不对称化合物,缩短了化合物上一条侧链的方法来降低分子的对称性。
We have synthesised unsymmetrical compounds through a "one-pot"process, achieving reduced symmetry by shortening one side chain of target compound.
依据液晶分子结构理论,选择联苯基作为介晶基元,六亚甲基为柔性间隔基,合成了一种丙烯酸酯侧链型液晶高分子。
Based on the liquid crystalline polymer theory, a kind of polyacrylate was synthesized by choosing biphenyl group as rigid nucleus of mesogenic unit and hexylidene as flexible spacing group.
本文从异黄酮侧链化学修饰出发综述了该类化合物衍生物的合成研究。
This research advance was summarized in synthetic methods of the isoflavone derivatives in chemical modification.
本文合成了侧链上带有酰胺基、羧基、酯基和羟基的水溶性聚丙烯酸树脂。
A water soluble acrylic coatings with amide, carboxyl, ester and hydroxyl group on side-chain have been synthesized.
通过接枝反应合成了一系列侧链含联苯类介晶基元的聚醚型树脂,并对合成工艺进行了探讨。
A series of polyether resins with pendent biphenyl mesogenic groups were synthesized, and the synthetic technics were discussed.
目的:合成头孢克肟侧链活性酯。
Objective: To study the synthetic technique of cefixime activated thioester.
首先以茄尼醇合成全反式侧链四十碳十烯-1-醇,再和2,3-二甲氧基-5-甲基-1,4-苯醌的还原产物在无水氯化锌存在下缩合。
All - E long chain part was synthesized from solanesol, then condensed with the reductive product of 2,3 - dimethoxy - 5 - methyl -1,4- benzoquinone in the presence of dry ZnCl2.
将柠檬酸作为侧基引入到聚羧酸大分子链中,合成了一种新型聚羧酸系高效减水剂。
A new polycarboxylic acid type superplasticizer was synthesized by introducing citric acid to polycarboxylic acid molecule as branch in order to solve concretes slump-loss, bleeding and segregation.
本课题概述了碳青霉烯类抗生素的研究进展,并设计合成了比阿培南的侧链中间体。
This paper studied some of the highlights in the progress of the research of carbapenem antibiotics, designed and mainly synthesized branched chain intermediate of biapenem.
在已经合成的螺旋聚合物中,具有主链共轭双键和功能侧基的取代乙炔类聚合物更是引起了广泛兴趣。
Among the synthetic helical polymers, polyacetylene derivatives with conjugated main chains and functional pendent groups, have gathered much more attention.
系统地综述了含柔性侧链苯并菲衍生物的合成方法的研究进展。
This paper reviews the synthetic methods for triphenylenes with flexible side chains.
并介绍了侧链型聚酰亚胺泡沫塑料以及聚酰亚胺纳米泡沫塑料的合成路线和制备工艺。
The synthesis route and preparation technology of the branch polyimide foam and polyimide nano-foam were introduced emphatically.
合成了三种新型的主链为聚4-乙烯基吡啶的侧链型紫精聚合物和相应的小分子紫精,研究了它们的电还原及光还原行为。
Three new types of side chain polyviologen, using poly 4-vinyl pyridine as main chain, were synthesized and their electroredox and photoreduction behaviors were investigated.
本文综述了侧链液晶聚合物(SCLCP)的合成方法;
The synthetic methods of side chain liquid crystal polymer(SCLCP) were described;
按照已有的酶活性中心的金属-氨基酸侧链配位和空间关系,设计合成多齿配体,并使配体和金属离子通过配位作用形成配合物。
They are designed according to the special relations and coordination of metal-amino acid side chain in the active centre in known enzymes.
本发明茼蒿素类化合物及其合成方法与应用,该化合物具有烯醇醚-螺环缩酮-缩醛和不饱和侧链。
The invention relates to garland chrysanthemum extract compounds, and a synthesis method and application thereof. The compounds have enol ether-spiro ketal-acetals and unsaturated side chains.
本发明以高收率高选择性地合成了一些新的长侧链双酚类化合物。
The said process can synthesize bisphenol compounds with long side chain in high yield and high selectivity.
以乙酰乙酸叔丁酯为原料,经过肟化、醚化、氯代酯解反应合成了头孢克肟开环侧链酸。
Cefixime open side chain acid was prepared by oximation, etherification, chlorination, ester decomposition using t-butyl acetoacetate as starting material.
以乙酰乙酸叔丁酯为原料,经过肟化、醚化、氯代酯解反应合成了头孢克肟开环侧链酸。
Cefixime open side chain acid was prepared by oximation, etherification, chlorination, ester decomposition using t-butyl acetoacetate as starting material.
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