正由于凋亡相关蛋白和细胞周期调节因子间的相互作用，使恶性肿瘤保持较高的细胞累积率。
It is because the reciprocal activation of apoptotic proteins and cell cycle control factors that maintain a higher cell accumulation rate in malignant tumors.
目的探讨小儿皮肤血管瘤各阶段肿瘤坏死因子相关凋亡诱导配体(TRAIL)的表达与细胞增殖和凋亡的关系。
Aim: to investigate the relationship between the expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), cell proliferation and apoptosis in children's skin hemangioma.
目的探讨肿瘤细胞表面dr5表达水平与其对肿瘤坏死因子相关的凋亡诱导配体(TRAIL)敏感性之间的关系。
Objective to investigate the correlation between sensitivity to tumor necrosis factor-related apoptosis inducing ligand (TRAIL) and expression level of death receptor 5 (DR5) on tumor cell surface.
目的：探讨肿瘤坏死因子相关凋亡诱导配体（TRAIL）联合化疗药物治疗神经母细胞瘤（NB）的作用及其可能机制。
Objective: To explore the role of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL) combined with chemotherapeutic agents in treating neuroblastoma(NB) and the possible mechanism.
肿瘤坏死因子相关的凋亡诱导配体(TRAIL)能选择性诱导肿瘤细胞凋亡。
TNF related apoptosis inducing ligand (TRAIL) can induce specific apoptosis of cancer cells.
许多转录因子、细胞内信号转导调节蛋白、炎症细胞因子和细胞凋亡相关基因的表达均发生了明显的调节变化。
The expressions of many genes encoding transcription factor, cytokines, cell signaling modulators and apoptosis associated proteins were found to have changed.
目的探讨脂多糖(LPS)、巨噬细胞表达肿瘤坏死因子相关凋亡诱导配体(TRAIL)和肝细胞凋亡的相互关系。
Objective to investigate the influence of lipopolysaccharide (LPS) on macrophages expressing TNF-alpha related apoptosis induced-ligand (TRAIL) and its relation to apoptosis of HepG2 cell line.
肿瘤坏死因子相关诱导凋亡配体(TRAIL)是TNF家族中的一个新型凋亡分子。
TNF related apoptosis inducing ligand (TRAIL) is a newly identified member of the tumor necrosis factor (TNF) family.
目的：探讨肿瘤坏死因子相关细胞凋亡诱导配体(TRAIL)对人卵巢癌细胞株体外生长抑制作用。
Objective: the study is to find out the inhibition action of TNF-related apoptosis-inducing ligand or APO-2ligand (TRAIL) on ovarian carcinoma cell line cultured in vitro.
目的：探讨肿瘤坏死因子相关诱导凋亡配体(trail)蛋白和顺铂协同抑制横纹肌肉瘤细胞生长和诱导凋亡作用及其机制。
AIM: to study the synergistic induction of apoptosis by TRAIL and cisplatin in rhabdomyosarcoma cells and investigate the role of mitochondrial membrane potential and caspase-3 in this process.
背景与目的：肿瘤坏死因子相关凋亡诱导配体（tumornecrosisfactor-relatedapoptosisinducingligand，TRAIL）有广谱的抗瘤作用，且对正常组织细胞无毒性，因此有望应用于肿瘤基因治疗。
BACKGROUND & OBJECTIVE: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells.
背景与目的：肿瘤坏死因子相关凋亡诱导配体（tumornecrosisfactor-relatedapoptosisinducingligand，TRAIL）有广谱的抗瘤作用，且对正常组织细胞无毒性，因此有望应用于肿瘤基因治疗。
BACKGROUND & OBJECTIVE: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells.
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