一些青少年已经转换了一个特定的基因——糖皮质激素受体（GR）——帮助调节体内荷尔蒙对于压力的反应。
Some of the teens had changed to one particular gene—the glucocorticoid receptor (GR)—that helps regulate the body's hormonal response to stress.
这种效应被认为是通过小梁网的糖皮质激素受体介导的。
The effect was thought to be mediated via trabecular meshwork glucocorticoid receptors.
地塞米松治疗组在治疗后期不能有效维持糖皮质激素受体活性。
Dexamethasone treatment had no obvious effect on GR activity during the late period of treatment.
研究者们进一步探究是什么造成了糖皮质激素受体基因表达的差异。
The researchers went on to study what is responsible for the difference in expression of the glucocorticoid-receptor gene.
这就可以解释为什么两组老鼠中的糖皮质激素受体蛋白水平会有差异。
This explains why levels of glucocorticoid-receptor protein are different in the two groups of rats.
这些作用不能被糖皮质激素受体(GR)拮抗剂ru 486所阻断。
RU486, an antagonist of glucocorticoid receptor (GR), did not affect these effects.
本文对糖皮质激素受体的生物学特征及其在眼科的研究进展作一综述。
In this article the biological characteristics and progress of research in ophthalmology about gr were reviewed.
本发明涉及式（I）的化合物或其盐，其是糖皮质激素受体的调节剂。
The present invention is directed to compounds of Formula I: (I) or salt thereof, which are modulators of the glucocorticoid receptor.
目的研究家兔糖皮质激素受体(GR)与激素性青光眼(SIG)的关系。
Objective to study the correlation between the rabbit glucocorticoid receptor (GR) and steroid induced glaucoma (SIG).
具有糖皮质激素受体结合活性的新型1，2，3，4-四氢喹喔啉衍生物。
Novel 1,2,3,4-tetrahydroquinoxaline derivative having glucocorticoid receptor binding activity.
在内源性激素存在的条件下，用交换法测定了大鼠肝胞液的糖皮质激素受体。
The glucocorticoid receptor of hepatic cytosol of rat was determined by the exchange assay in the presence of endogenous corticosterone.
前言：目的：研究寒、热证豚鼠变应性鼻炎糖皮质激素受体(G CR)活性。
Objective: to study on glucocorticoid receptor (GCR) activity of peripheral leukocytes in allergic rhinitis guinea-pigs with Cold or Heat Syndrome.
免疫共沉淀法检测核蛋白中BAG-1与糖皮质激素受体（GR）的相互结合；
The interactions between BAG-1 and glucocorticoid receptor(GR)were detected with immune co-precipitation.
例如，糖皮质激素受体基因在大脑特定区域的持续表达提高了调节应激反应的能力。
For example, increased expression of the glucocorticoid receptor gene in particular brain regions improves the ability to regulate a stress response.
研究表明，糖皮质激素受体在应激反应和炎症反应的调控中起着非常重要的作用。
It was reported that the glucocorticoid receptor played a key role in regulation of stress and inflammation response.
当研究人员改变早先的原始受体的这7个位点后，它就成为了一个新的糖皮质激素受体了。
When he made these 7 changes to the ancestral receptor, it behaved just like a new glucocorticoid receptor.
到目前为上的假说是：脑内某些区域如海马中糖皮质激素受体的改变可能引起抑郁症状。
It has been hypothesized that changes in the glucocorticoid receptors in certain regions of the brain (eg, the hippocampus) might contribute to the depressive symptoms.
糖皮质激素(GC)现已广泛用于临床，通过糖皮质激素受体(GR)介导产生生物效应。
Glucocorticoid (GC) has been widely used now and it binds to glucocorticoid receptor (GR) to produce its biological effect.
该单克隆抗体是由对应人糖皮质激素受体蛋白靠近氨基末端残基的重组蛋白免疫动物而生产的。
Monoclonal antibody is produced by immunizing animals with a recombinant protein specific to the amino terminus of human GR protein.
目的探讨重症肌无力患者外周血白细胞糖皮质激素受体含量与应用糖皮质激素治疗效果的关系。
Objective to investigate the relationship between the contents of glucocorticoid receptors (GCR) in myasthenia gravis and the curative effects of steroid therapy.
结论：江西籍汉族人种中糖皮质激素受体基因外显子2/1密码子23基因未发现多态性的存在。
Conclusion: No correlation was found between glucocorticoid receptor gene in exon 2/1 codons 23 and asthma.
糖皮质激素受体的下调提示可能与患者机体应激反应紊乱，以及肝衰竭不同时期免疫状态的改变有关。
It is possible that glucocorticoid receptor down-regulation indicates disorders of stress response and also may be associated with altered immune status of patients with ACLF of different stages.
研究发现，孕期中遭到虐待的母亲生下糖皮质激素受体基因被甲基化的幼儿的可能性要比其他母亲高出得多。
They found that women abused during pregnancy were significantly more likely than others to have a child with methylated glucocorticoid-receptor genes.
中医药在调节糖皮质激素受体方面也进行了许多探索，为中医药作用机制研究奠定了现代生理病理学基础。
The exploration on the regulation of traditional Chinese medicine on GR has established a modern physiological and pathological foundation for research of traditional Chinese medicine.
目的探讨多发性硬化(MS)患者外周血白细胞糖皮质激素受体(GR)含量与糖皮质激素的治疗效果关系。
Objective to explore the relationship between the contents of glucocorticoid receptors (GR) in multiple sclerosis (MS) patients and the efficacy of steroid therapy.
由于糖皮质激素受体的存在，几乎所有的细胞，无论是理想和不受欢迎的糖皮质激素治疗的影响是多方面的。
Due to the presence of glucocorticoid receptors in almost all cells, both the desired and undesired effects of glucocorticoid therapy are manifold.
结论慢加急性肝衰竭患者外周血cd3 +T淋巴细胞糖皮质激素受体的下调，与患者升高的皮质醇有关。
Conclusions Glucocorticoid receptors are down-regulated in CD3 + t lymphocytes in association with increased adrenal secretion of cortisol in ACLF.
一些母亲在怀孕时一直处于忧伤抑郁的情绪中，她们的孩子在刚出生时甲基化糖皮质激素受体水平就远高于常人。
Newborns whose mothers suffered from depression while they were pregnant are known to have more highly methylated glucocorticoid-receptor genes than others.
他们的团队对一组10到19岁的儿童进行了糖皮质激素受体基因甲基化的检测，并对他们的妈妈做了同样的检测。
Their team examined the methylation of the glucocorticoid-receptor gene in a group of children ranging in age from ten to 19 years, and in those children's mothers.
他们的团队对一组10到19岁的儿童进行了糖皮质激素受体基因甲基化的检测，并对他们的妈妈做了同样的检测。
Their team examined the methylation of the glucocorticoid-receptor gene in a group of children ranging in age from ten to 19 years, and in those children's mothers.
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