Toxicity would probably be worse in frail and vulnerable patients, and these regimens "should be administered with caution or not at all in such patients, " they add.

他们附带表示，这些毒性对于更虚弱或是更高龄的患者而言，将会是更糟的，这些疗程应该小心使用，它并非适用于所有此类病患。

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Toxicity would probably be worse in frail and vulnerable patients, and these regimens "should be administered with caution or not at all in such patients, " they add.

他们附带表示，这些毒性对于更虚弱或是更高龄的患者而言，将会是更糟的，这些疗程应该小心使用，它并非适用于所有此类病患。

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