Crisis in the development of new antimicrobials.
开发新抗菌素方面的危机。
Antimicrobials are different from other medicines.
抗菌素与其它药物不同。
Objective To enhance rational use of antimicrobials and decrease drug abuse.
目的：加强抗菌药物的合理应用和减少药物滥用。
The antibacterial mechanism of this kind of inorganic antimicrobials is proposed.
对该类抗菌剂的抗菌机理作了初步分析。
As the century progressed, more and more first - and second-line antimicrobials failed.
随着本世纪的进展，越来越多的一线和二线抗微生物药物失效。
A second concern is that there is no significant new drug development for antimicrobials.
第二项关注是，在抗菌素方面没有显著的新药开发。
METHODS P. aeruginosa resisted to 10 sorts of antimicrobials was detected by K-B method;
方法K-B法测定铜绿假单胞菌对10种抗菌药物的耐药性；
Misuse of antimicrobials in the past and today threatens the welfare of future generations.
过去和今天滥用抗菌素的做法威胁到子孙后代的福祉。
Irrational and inappropriate use of antimicrobials is by far the biggest driver of drug resistance.
抗菌剂的不合理及不当使用，目前是出现耐药的最主要原因。
OBJECTIVE To find out about the transverse section use rate of antimicrobials in our hospital.
目的了解医院抗菌药物横断面使用情况。
This is not at all what is happening, with the pipeline for new antimicrobials all but dried up.
但现实非同所想，研制新抗生素的渠道已几乎全部枯竭。
Irrational and inappropriate use of antimicrobials are by far the biggest drivers of drug resistance.
对抗菌素的不合理和不当使用是迄今导致药物耐药性出现的最大驱动因素。
RESULTS: The irrationality of 16 kinds of combined use of antimicrobials was summarized and analyzed.
结果：归纳出16类不合理联用抗菌药情况。
Antimicrobials are generally relatively safe when compared to other medicines used to treat human disease.
与用于治疗人类疾病的其它一些药物相比，抗菌素一般比较安全。
When the microorganisms become resistant to most antimicrobials they are often referred to as "superbugs".
当微生物对多数抗菌素产生耐药性时，它们常常被称为“超级细菌”。
Results Pharmacodynamic parameters of antimicrobials play an important role on interval time using medicine.
结果抗菌药物药效学参数对确定给药间隔时间有重要作用。
Resistance to mainstay antimicrobials is occurring at a rate that outpaces the development of replacement drugs.
主要抗菌素耐药性的出现速度超过了研制替代药物的速度。
This paper briefly introduces the sources of natural antimicrobials and their application in food preservation.
介绍了天然抗菌物的各种来源及其在食品防腐中的应用现状与应用潜力。
Objective To discuss the effect of pharmacodynamic parameters of antimicrobials on interval time using medicine.
目的探讨抗菌药物药效学参数对决定给药间隔时间的作用。
As a survival mechanism, other microbes have developed mechanisms for resisting the toxic effect of antimicrobials.
作为一种生存机制，其它微生物产生出抵御抗菌素毒性作用的机制。
Most "new" antimicrobials are chemical variants of older agents. Consequently resistance development can occur quickly.
多数“新”抗菌素是老药剂的化学变种，因此，可能迅速出现耐药性。
OBJECTIVE: To evaluate the therapeutic efficacy of rational use of antimicrobials with the aid of clinical pharmacists.
目的：评价临床药师协助临床合理应用抗菌药物的效果。
Results:After intervention, the utilization, cost and preventive usage of antimicrobials decreased significantly(P0.01).
结果：干预后抗菌药物的使用率、抗菌药费、预防性用药的比率等均有明显下降（P〈0.01）。
This discovery could help us find novel antimicrobials for human use and lead to more effective strategies for using them.
这个发现有助我们找到可用于人类的新型抗菌素，从而得到更有效的使用抗菌素的方法。
Results: More antimicrobials resulted in fever in 12 patients, even more than one drug responsible for the fever in 6 cases.
结果：12例患者分别对氧哌嗪青霉素等抗菌药物产生了药物热，其中6例对多种抗菌药产生药物热。
Antimicrobials are typically used for a period of one to ten days, decreasing the financial incentive for new drug development.
抗菌素的使用期限一般为1 -10天，这削弱了新药物开发的经济动力。
Who is minding the “commons” in terms of the overuse and misuse of antimicrobials in the veterinary, agri-food and human settings?
就抗菌素在兽医、农产品和人类环境中的过度使用和滥用而言，有谁在照料“公地”？
In humans, our misuse of antimicrobials is causing mainstay drugs to fail much faster than the pace of development of replacement drugs.
就人类而言，我们滥用抗菌剂导致主流药物迅速失效，速度远远高于研制替代药物的速度。
And this includes the massive routine use of antimicrobials, to promote growth and for prophylaxis, in the industrialized production of food.
它还包括在食品工业化生产中大量常规地使用抗菌剂来促进生长和防病。
And this includes the massive routine use of antimicrobials, to promote growth and for prophylaxis, in the industrialized production of food.
它还包括在食品工业化生产中大量常规地使用抗菌剂来促进生长和防病。
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