But the biotech sector has tremendous growth potential, so some investors with a big appetite for risk may want in.
On the other hand, my personal view is that the Pakistani government doesn't have a big appetite to go after bin Laden.
"Last year the World Championship reached 18.7 million people across the tournament, showing there is a big appetite for the sport, " he added.
Investors have also had a big appetite for Chinese telecommunications stocks.
The British Paralympic Association said high ticket sales showed a big public appetite for Paralympic sport.
BBC: London 2012: Paralympics divide opinion, survey suggests
Saudi Arabia's stock market has risen strongly in recent months, creating a "big appetite for shares", said Mr Goussous.
Unfortunately, there is no assurance that a new round of fiscal stimulus would be effective, there is little appetite among legislators for a big new package, and the likelihood of pushing one through the new, divided Congress is doubtful.
Britons do seem to regard climate change as a problem, but there is little appetite for big lifestyle changes.
China has a big surplus with America which reflects America's appetite for cheap Chinese goods but its global trade is roughly in balance.
The big surprise would be a change to market risk that could increase an appetite for JPY and in-turn squeeze the weaker and most vulnerable of JPY shorts.
Although new CAFE standards should encourage the shift away from the thirstiest models, trucks still get off too lightly and the administration seems to have no appetite for the one thing that would radically change buying habits: a big increase in petrol taxes or a more widely applied tax on carbon.
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