Sirtris Pharmaceuticals, a firm based in Cambridge, Massachusetts, of which Dr Sinclair is a co-founder, has identified a number of synthetic molecules whose effect on yeast is many times more potent than resveratrol's.

ECONOMIST: How to live longer��maybe

"Pal Joey" is one of the all-time great Broadway musicals, a portrait of life on the bottom rungs of showbiz in which Richard Rodgers and Lorenz Hart teamed up to immensely potent effect with John O'Hara ("Appointment in Samarra"), who wrote the book.

WSJ: 'Woman in Mind': Funny as a Straitjacket | Eclipse Theatre Company | Pal Joey | Porchlight Music Theatre | Reviews by Terry Teachout