Pharmaceutical companies have made a habit of targeting the wrong cause (acetylcholinesterase inhibitors which are basically useless since as the disease progresses acetylcholinesterase activity declines by 85 percent), one aspect of the disease (Namenda as an antagonist for NMDA receptors), or insisting on a partially flawed mechanism for the disease (amyloid plaques).
FORBES: Pharma's Reputation Continues to Suffer -- What Can Be Done To Fix It?