For all Genzyme's stability, its gene therapy research might represent a kind of Achilles' heel.
The Players' Achilles' heel, however, is that it is still essentially a PGA Tour tournament.
Every couple has its Achilles' heel, that pressure-cooker situation that brings out the worst in two people.
Wales became penned back in their own half because of their other Achilles' heel - the line-out.
However, government bonds have a significant Achilles' heel: Whenever rates rise, they will take the biggest hit.
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Ms. ANDERSON: Republicans will give the appearance of contesting for African-American vote because they've remained the Republican Party's Achilles' heel.
The scandals nonetheless made clear that the Catholic Church's lumbering, centuries-old Vatican administrative bureaucracy is its Achilles' heel.
This specificity is essential but it is also its Achilles' heel - because these viruses are masters of disguise.
If Huckabee has an Achilles' heel, it's his lack of experience, Holland said.
But then the price of the edible oils used in many of its products--the Achilles' heel of the food distribution business--started gyrating.
Online, America's aching Achilles' heel is the wide-open automated control systems that run the nation's networks for electricity, water, gas, oil and more.
Bush's lack of experience has long been his Achilles' heel, but it was never so apparent -- because Gore never made it apparent.
Mr. Horn's lack of digital-age expertise could be his Achilles' heel.
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For Spencer, the need for glasses could be 3-D's Achilles' heel.
McCain has a long list of endorsements, but immigration continues to be his Achilles' heel because of his support in the Senate of unpopular reform legislation.
But he said attacks like those will prove to be the jihadists' "Achilles' heel, " turning the population against them and driving them toward the concerned citizens' groups.
One "more likely than not" opinion written for this shelter ignores what experts call its Achilles' heel: the relationship between the leased employee and the organization he's ultimately leased back to.
Until now, index funds have had an Achilles' heel.
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Morris says he favors new renewable sources, but the "Achilles' heel" for solar and wind is the fact that the sun shines brighter and the wind blows harder in the West and Great Plains.
The telescope mission has more than one Achilles' heel: it cannot be serviced by astronauts, as Hubble was, once it is in space, and it cannot be returned to Earth once it is launched.
That makes the antibodies useful weapons in attacking the virus' Achilles heel, and a potentially powerful target for an effective vaccine.
Anuzis' Achilles heel is his record in Michigan, where he can point to few gains among Republicans in the battleground state since taking over the state party in 2005.
So it is clear that Israel cannot simply turn its back on the free world's Achilles heel.
"Water is the nuclear industry's Achilles heel, " Jim Warren, executive director of N.
The bad loans this generates are the system's Achilles heel.
"I see England's big Achilles heel as being the top order, " he says.
Dr Manning said that region may have been the dinosaur's "Achilles heel".
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