At the same time, within the big markets, a range of new genres hip-hop, trip-hop, lounge, acid house, acidjazz, and many, many more are growing at the expense of the mainstream.
When Orphan Medical, which was later bought by Jazz, filed its new drug application with the FDA, the street drug gamma-hydroxybutyric acid (GHB) was in the news as a date-rape potion and drug of abuse.