In addition, results presented last year for our monoclonal antibody solanezumab support the amyloid hypothesis.
An injectible antibody for a target protein called CTLA4 has shown promise in melanoma.
It was an antibody that primes the immune system to attack and kill tumors.
It is a human monoclonal antibody that attacks the toxins anthrax bacteria spew out.
These men experienced an immunological firestorm in that the antibody caused the uncontrolled release of toxins.
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To create LymphoStat-B, HGS devised an antibody that binds to BLYS and inactivates it.
In 1994 the University of Paris' Lucienne Chatenoud tried treating diabetic mice with Bluestone's antibody.
ImClone's Erbitux blocked the EGF receptor in a slightly different way, using an injectable monoclonal antibody.
The Pfizer antibody shrank melanomas in 7 of 84 patients in a midstage trial.
The cancer cell, considering the antibody an ally, pulls the compound into its interior.
In 1990 he and colleagues gave this antibody to rats with severed spinal cords.
Before chemotherapy, tumor cells are taken from each patient and then fused to antibody-producing mouse cells.
Even more intensely awaited are the results of a second-stage trial of Wyeth's antibody, bapineuzumab.
Two months later Fishman hired rheumatologist Wright, who proposed testing Novartis' own antibody in Muckle-Wells.
Lieberburg is mum on some details of the vaccine and the antibody for intellectual property reasons.
Now the second NGF-1 antibody, from Regeneron and Sanofi-Aventis, has been put on ice, too.
When the CDX-011 antibody attaches to GPNMB-expressing tumor cells, it releases a toxic chemotherapy payload.
An antibody is a protein that has been tailored to stick to just one sort of molecule.
This was turned into a cancer test by attaching small amounts of radioactive material to the antibody.
By 1993 the company had designed a monoclonal antibody to VEGF that slowed tumor growth in animals.
Pfizer is also stopping its efforts in dermatology and gastroenterology, and moving into antibody drugs and vaccines.
It specifically targets the antibody immunoglobulin E (IgE), which is involved in the allergic process in asthma.
Denosumab is an antibody that blocks the RANK ligand, a protein that tells the body to remove bone.
After just a few days a few leaves are taken, ground up, and the antibody extracted from them.
We know that people who have survived an anthrax challenge have developed antibody from reports in the literature.
Genentech unit is looking into another monoclonal antibody called crenezumab that also targets plaque buildup in the brain.
Among the furthest along in the pipeline is a monoclonal antibody called elotuzumab from Bristol-Myers Squibb Co.
That happens when the antibody that is attached to the invader also attaches itself to an Fc-receptor molecule.
The firm's researchers can produce billions of viruses, each with a different binding site from a human antibody.
At the moment, however, picking the antibody appropriate to a particular disease is still something of a craft.
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