The agency awarded a contract several weeks ago to five manufacturers to develop an H1N1 antigen.
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We began promoting and using the prostate-specific antigen test before it had been adequately evaluated.
In this case, a little genetic engineering convinced vaccinia to produce an important rabies antigen.
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Structures called variable novel antigen receptors (VNARs) are found in the shark immune system.
Both drugs turn off a natural brake on immune system activity called CTLA4 (cytotoxic T-lymphocyte antigen 4).
Last month the task force advised against routine prostate-specific antigen (PSA) tests to screen for prostate cancer.
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They acquired Whale Communications in 2006 and Sybari Antigen in 2005.
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Well, there is a reference to the pain of the test itself, presumably the PSA (Prostate Specific Antigen) test.
Men who get tested for prostate specific antigen, or PSA, have a 13.5% chance of landing in the danger zone.
Personally, I favor the vaccine being developed by Antigen Express to gain a partner after they pass a couple more milestones.
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Out of tens of thousands of proteins in a cancer cell, less than one in a thousand may become a cancer antigen.
For a T cell to become active, it must receive signals from another part of the immune system called an antigen-presenting cell.
On the side, he took part in an international workshop studying the human leukocyte antigen gene complex, which helps regulate the immune system.
In the last few years, there has been some pushback against the potential over-use (and detriment) of mammograms and prostate specific antigen tests.
As the tip continued its movement across the surface, the antibody was snapped off the antigen and dragged along until it hit another receptive site.
The vaccine was created by taking a glycoprotein antigen from the rabies virus and inserting it into Vaccinia virus, the same one used for smallpox inoculation.
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To do this, they used antibodies designed to bind to and thus decommission the molecules on T cells that are used to shake hands with antigen-presenting cells.
One strategy is to look not for the antigen itself but for certain helper proteins, called chaperones, that bring the antigen to the attention of the immune system.
In May 2012, the U.S. Preventive Services Task Force recommended against routine PSA screening (Prostate-Specific Antigen test to screen Prostate cancer) before being diagnosed as it did not benefit patients.
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In addition, 54% of MDV3100 patients compared to 1.5% of those on placebo had a greater than 50% reduction in a marker called prostate specific antigen an indicator of a positive response to the drug.
Pfizer's drug tremelimumab and Bristol-Myers Squibb's ipilimumab are antibodies to a protein called CTLA-4 (cytotoxic T-lymphocyte antigen-4) that acts as an emergency brake to prevent killer T cells from attacking healthy tissue.
However, before the alarm can be sounded in this way, proteins on the surface of the antigen-presenting cell and the T cell must bind together in what is called a cellular handshake.
Antigen-presenting cells collect fragments of proteins from foreign bodies (normally pathogens, such as viruses and bacteria, but also transplanted organs) and show these to T cells, in order to tell them what to attack.
Shan Wang of Stanford has used a GMR chip smaller than a postage stamp to detect carcinoma-embryonic antigen (a sign of colon and rectal cancer) and human papilloma virus, the main cause of cervical cancer.
Fortunately, earlier diagnosis of prostate cancer, thanks to prostate-specific antigen (PSA) testing, may have slowed and even reversed these trends, according to the study, which was published in the Journal of the National Cancer Institute.
So it ought to be possible to test for the presence of a certain antigen on a surface by dragging a suitable antibody over it, and seeing if it gets stuck going fishing, in effect, on a molecular scale.
The biotechnology firm announced that a much-awaited study of its bone drug Xgeva (also known as denosumab, and sold for osteoporosis as Prolia) prevented prostate cancer from spreading to the bone in patient whose levels of prostate-specific antigen are rising.
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But UC David professor Michael Wilkes investigated and learned that the seminar was primarily a sales pitch about the prostate specific antigen (PSA) test, and that its main message was that men should get tested regularly beginning at age 40.
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Dr Hinterdorfer and his team tested this idea by applying a coating of an antigen (an enzyme called lysozyme) to a mica sheet, and suspending an appropriate antibody from the tip of an atomic-force microscope with a flexible polymer tether.
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