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Two better-known alternatives, antisense and RNA-interference, the latter of which is being used now by Monsanto, can silence or shut down genes but cannot turn them on or make them louder.
FORBES: Magazine Article
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By binding to RNA, antisense prevents proteins involved in disease from ever being created.
FORBES: Magazine Article
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Antisense instead binds to the RNA messenger molecules that ferry genetic information from the DNA to the cell.
FORBES: Magazine Article
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The goal was to jam the works by synthesizing an antisense strand of DNA to gum up the RNA section that codes for PKC-alpha.
FORBES: Antisense and Sensibility
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When Isis' antisense strand latched on there, it activated an enzyme that destroys the RNA that codes for PKC-alpha.
FORBES: Antisense and Sensibility