Wigan's Julius Aghahowa replaced the injured AntoineSibierski five minutes into the half and was booked just six seconds later after clattering into Campbell.
Wigan, who have yet to score a league goal against Liverpool, gave Nigerian international striker Aghahowa his first start up front in place of the injured AntoineSibierski.
City's form deserted them drastically as McIndoe, James Coppinger and Paul Heffernan all scored for the hosts while Vassell hit the bar before Budtz saved from AntoineSibierski and Dunne to take the hosts through.