In Roman times the averagelifespan was just 22 (mainly because of the appalling rate of infant mortality), by 1800 it was 40 years, 1900 around the late 40s and today it hovers around the mid-to-late 70s.
These patients have a 25 times greater risk of kidney failure, heart attacks, strokes and blindness, and have an average of 15 years sliced off their lifespan.