Given the high prices of rare disease drugs, sales could be big if enough patients can be found.
That's a big if--and it masks a series of troubling decisions the founders have made almost since the beginning.
If that has changed - and that is a big if - then the pound could well fall in 2013.
Yet in tsunami-hit Sri Lanka, where there was a large existing microcredit network, it has played a big if controversial role.
Mayweather has a chance to top that if, and it is a big if, he fights six times over the next two-and-a-half-years.
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Today, a 12-hour pass on the vaporetto is 16 euros, and you will be fined big if you try to game the system.
In 1998, France broke the spell that confounds teams like the NBA's Utah Jazz: being unable to win big if named after a musical style.
If they keep to these targets (admittedly a big if), they will have to restrict car use, which will reduce in turn their imports of oil.
We fear this proposal, if it makes it through both the Senate and the House (admittedly a big if), will create a different set of problems all together.
If that happens--and that's a big if--iPod rivals should benefit.
And going forward, if -- big if -- you can get a deal on this, can you get anything done with Congress for the next year and a half?
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If Congress does manage to pass the current package of proposals (a big if, going by its past record), Brazil's court system would benefit from a radical and belated overhaul.
Assuming these efforts succeed, and that's a big if, health care in the U.S. could begin to look a lot more like the centrally controlled systems of Canada, the U.K. and Europe.
If Mr. Obama responded forcefully and effectively - a big if, but not out of the question - Republican prospects this Fall might be considerably different than they seem at the moment.
Even if senators can finalize a deal soon on the structure of a consumer protection authority--and that's a big if--it could be weeks before a financial regulatory bill comes to the Senate floor for a vote.
If (still a big if) hiring by firms picks up sharply in coming months, pushing up incomes, then consumers will become less reliant on asset appreciation and debt, and the recovery will become more soundly based.
But even if the leaders have silenced questions about debt restructuring in other countries (and that is a big if), they may have done so only at the cost of keeping the question wide open for Greece.
If treasury bills are without default risk (a big If in these times), and corporate bonds do have default risk, then corporate bonds are less valuable than treasuries to the degree that the default risk rises or falls.
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"If they have any -- and still, that's a big if -- I would doubt that they would use it because a lot of countries and people in the world are negative to the idea of waging war, " Blix said.
If such a reactor could meet the targets claimed for it by its proponents (a big if, says Harvard's Mr Bunn), it has the potential to be cheaper than existing types of nuclear energy, safe from Chernobyl-style large accidents, and more proliferation-resistant than typical reactors.
Then if, and I it is a big if, a judge and jury can be shown that the relative importance of the MGT patent to casino operations is proportionally much greater than that of Vringo patent to Google, maybe the royalty could be more significant.
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The message is that if - and it is still a big if - the Greek government is able to pass that austerity package in the next few days, the eurozone will fulfil its side of the deal by coming up with a structure for a second Greek bailout, which Germany and everyone else can support.
The investment money from the Gulf, China and Singapore will help avert a recession in the U.S. if, and a big "if" here, the funds are welcomed.
With the Auction House feature of Diablo III now live, Donovan said Blizzard can make a big statement if they can keep a big user-base and run the real-money auction house.
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