The goal: a drug against osteoporosis, the brittle-bone disease that afflicts 25 million older Americans, mostly women.
But far worse, it melted at high temperatures and became brittle at low ones.
Set against successful replanting of low-lying bushes, the dead and brittle trees are strangely beautiful.
But a number of recent events suggests the country often has a brittle relationship with foreigners.
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The resulting aerogel blanket was flexible rather than brittle, which solved the handling problem.
Thirty years ago some contractors used brittle PVC pipes that burst when they froze.
"Technology is brittle, " said Jaime Punishill, an analyst at Forrester Research Inc. in Cambridge, Mass.
Ms Cutland highlighted the case of Casey Brittle, who was murdered by her former partner.
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Bone mineral density may be compromised by tobacco, making bones more brittle and break-prone.
Natural-gas pipelines cannot be used because hydrogen makes the steel tubing brittle and attacks the welds.
For dessert, the Milk and Honey shortbread, brittle and ice (an Eleven Madison classic) was great.
Annette Bening may also be considered for Oscar gold for her portrayal as his brittle wife Carolyn.
As brittle and imperious as Bishop could be, she also could be a warm and considerate friend.
But Motorola is also exhausting them, as its patent legacy looks more brittle than Google anticipated.
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The discussion touched on data which suggested that the O-rings might be more brittle at lower temperatures.
"It's a certain kind of sound that is a bit brittle and a bit nasal, " she said.
Have them replaced whenever they appear cracked, brittle, frayed, become loose or show signs of excessive wear.
Theron's brittle executive officer is just too close to caricature, and she's not the only one either.
But raising rates could break China's brittle state enterprises and lure in more speculative capital from abroad.
It has many brittle areas, such as management of its name space, compared to the best enterprise software.
But there are rules that can make it easier to cope with the failures of such brittle technologies.
As a fighting force, European countries will prove a brittle cane on which to lean in operations abroad.
While LCD screens have made major strides, they have two inherent problems: They gulp energy and are extremely brittle.
And, he goes on, reaching out to other groups in society might now smash the party's brittle bone structure.
Other studies have suggested statins can protect against Alzheimer's and even brittle bones.
In die-casting, the alloys tend to be brittle and have poor wear resistance.
Or it could go the way of Turkey, and evolve into something less brittle and happier for all concerned.
They all contain whites, and yolks and are enveloped in thin, brittle shells.
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Kabardino-Balkaria now looks as brittle and unstable as Ingushetia and Dagestan, Chechnya's other neighbours, where shoot-outs and killings abound.
Kenya is east Africa's most dynamic country but it remains a brittle construction left behind by British colonial rulers.
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