But the benefits of calorie restriction require that mice live on a restricted diet for most of their lives.

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Dr Rattan also doubts whether calorie restriction will extend maximum human life expectancy.

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Other hormetic agents are, in mild doses, sunlight (vitamin D), fasting (calorie restriction) and their molecular mimic, red wine (resveratrol pills).

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People on either of the calorie restriction diets had reduced average core body temperature, which has been previously suggested to be an aid to living longer.

BBC: NEWS | Health | Low-cal diet 'long-life benefits'

Jeffrey Keller, a professor at Pennington Biomedical Research Center in Baton Rouge, Louisiana, who studies aging, metabolism, and neurodegeneration, agreed that seeing results after such a relatively short period of calorie restriction was surprising.

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After six months, the non-diet group had lost an average of 1% of their weight, the calorie restriction group, 10.4%, those who were on a calorie restricted diet plus exercise, 10% and the very low-calorie diet, 13.9%.

BBC: NEWS | Health | Low-cal diet 'long-life benefits'

The findings add to growing evidence that calorie restriction can benefit health and longevity, but this shouldn't prompt already skinny seniors to start dieting, said Carol Greenwood, a senior scientist and assistant director of the Kunin-Lunenfeld Applied Research Unit at Baycrest, a Toronto academic medical center focused on aging.

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