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Researcher Paolo Paoletti now heads cancer drug development at GlaxoSmithKline.
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Until now, OSI had only one major drug in development: Tarceva, a cancer drug that it is developing with Roche and Genentech (nyse: DNA - news - people ).
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Chief Executive StanleyCrookeStanley Crooke, 60, headed drug development at Smithkline Beckman and anti-cancer research at Bristol-Myers Squibb.
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The drug, developed through Cancer Research UK's Clinical Development Partnerships (CDP), starves cancer cells of the sugars they need to grow and develop.
BBC: Sir Bobby Robson and Ruth Plummer
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Chief Executive Stanley Crooke , 60, headed drug development at Smithkline Beckman and anti-cancer research at Bristol-Myers Squibb (nyse: BMY - news - people ).
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Therapeutic cancer vaccines, which train immune cells to attack cancer cells, are one of the most enticing areas of drug development.
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They already have contributed to the development of the antibiotics erythromycin and tetracycline, the cancer chemotherapy drug doxorubicin, Wyeth's transplant drug Rapamune, and Merck's cholesterol-lowering medicine, Mevacor.
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She said the findings were not just important for drug development, but also for developing a test which can predict the likelihood of cancer spreading and as a result, patient outcomes.
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Apart from its anti-cancer drugs Fusilev and Zevalin, Spectrum has 10 other oncology drug candidates that are now in clinical development, two of them in phase 3 clinical trials and several undergoing phase 1 and 2 clinical studies.
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Charles Baum, who heads Pfizer's oncology development program, says cancer drugs now account for 20% of the money Pfizer is spending on drug testing.
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