The connection between cholesterol and cardiovascular disease is by now so well established that inflammatory markers like CRP, while they may prove useful to test and treat, will not take the place of cholesterol any time soon, says Alan Daugherty, PhD, the director of the Cardiovascular Research Center at the University of Kentucky.

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"I think it's unlikely that further barking up the tree of LDL is going to show a substantial benefit, " says Allen Taylor, chief of cardiovascular research at Walter Reed Army Medical Center.

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"I wouldn't be surprised if COURAGE, as designed, is a negative trial, " Gregg Stone, director of cardiovascular research and education at Columbia University Medical Center, said two weeks ago.

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"I wouldn't be surprised if COURAGE, as designed, is a negative trial, " says Gregg Stone, director of cardiovascular research and education at Columbia University Medical Center, who has conducted major clinical trials of Boston Scientific's stent.

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Dr. Robert Michler, chairman of Cardiovascular and Thoracic Surgery at Montefiore-Einstein Heart Center, said the data should act as a "wake-up call" for physicians, surgeons and patients.

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The time it took for ambulances to arrive on the scene was similar for men and women, according to researchers at the Institute for Clinical Research and Health Policy Studies at Tufts Medical Center in Boston, Massachusetts, who published the study in the journal, Circulation: Cardiovascular Quality and Outcomes.

CNN: Five ways to get ambulance workers to take you seriously