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Her lawyers say the hospital failed to diagnose cauda equina syndrome, a spine condition, and operate before it was "too late to prevent permanent damage".
BBC: Debbie Thomason
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Michelle Chapman, 45, from Melton, went to the Leicester Royal Infirmary (LRI) in May 2007 with suspected cauda equina syndrome - a type of nerve damage.
BBC: Cauda equina syndrome misdiagnosis woman payout
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Ms Chapman had been suffering from numbness in her legs and her GP alerted her to cauda equina syndrome, where pressure on the base of the spine affects major nerves.
BBC: Cauda equina syndrome misdiagnosis woman payout
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"Cauda equina syndrome has devastated her life, but the tragedy is that it doesn't have to cause such significant disability and can be treated effectively with urgent surgery, " JMW lawyer Eddie Jones said.
BBC: Debbie Thomason