Dr. Chari recalls hunting for a molecule with "1, 000-fold more killing power" than the typical cancer agent.
WSJ: Drug Conjugates: 'Guided Missiles' to Treat Cancer
Dr. Chari set out to tweak this structure to enhance its linkage properties.
In 1986, Dr. Chari pored over a list of 3, 400 possible agents before finding two that seemed to be potent enough.
To make sure the few drug conjugates that reached their prey would destroy them, other researchers like Ravi Chari looked for compounds that were far more potent than standard therapies.
应用推荐
模块上移
模块下移
不移动