An average of 65 people per year in all of New York City contract the disease, according to the NYCHD.
Lorry drivers using prostitutes take the disease from one city to another.
The disease would skip from city to city over an 18- to 24-month period, infecting more than a third of the population.
The city-state maintains a strict disease and mosquito surveillance regime, as well as tough penalties for residents who fail to clear mosquito-breeding sites in their homes.
Many of the maples now being devoured by China's beetles were planted by his father, also Chicago's mayor, when Dutch elm disease swept through the city nearly three decades ago.
But even in this paradise, away from the city, with its dense population, disease and social ills, the villagers can relate to the same matter, and that residents of large cities ...
As for his record on AIDS, activists attack him for moving too slowly to marshal city resources against the almost-always fatal disease largely affecting gay men that began to take hold in the early 1980s.
WSJ: Ed Koch Legacy: New York City's Fortunes Improved Under His Leadership
An employee at NBC 's 30 Rockefeller Center building in New York City developed a skin-based version of the disease.
That is why experts at a medical conference in the city last month pressed for urgent evaluation of the disease's social impact.
Gareth Colfer-Williams, 25, died last week at his home in Swansea, the city at the centre of an epidemic of the disease which has reached 942 cases.
Jewish refugees were later herded into Hongkou ghetto in the city's northeast, where food was scarce and disease rampant.
Norman Collier died at a residential care home close to his home city of Hull after being ill with Parkinson's disease for a number of years.
So far, many public estimates have said that perhaps a tenth of the tens of thousands of people who are trapped in the city might suffer from post-traumatic stress disorder, a disease that raises the risk of suicide sixfold.
For example, 35 epidemiologists from the Centers for Disease Control and Prevention initially came to help New York City hospitals cope with the emergency.
Both theatres were built outside the city walls after players were formally expelled from London in 1575 to protect against disease and poor morals.
How did a virus that sprang from chimpanzees in Cameroon touch off a new disease first noticed among gay men in Los Angeles and New York City?
Disease and hunger too have begun to take a toll, as the city is cut off from outside aid.
The Centers for Disease Control (CDC), along with a growing number of state and city health departments, are reporting some of the highest numbers of affected individuals in recent history.
Some 34% of the survivors who were trapped inside the Murrah building in Oklahoma City when it was blown up came down with post-traumatic stress disorder, a disease in which patients can suffer from flashbacks, heightened anxiety and social withdrawal, according to surveys done by North.
Dr Alison Brind, consultant physician at the City General Hospital in Stoke is also heading research into genetic factors in alcohol-related liver disease.
Harry Moroz over at Next American City and Richard Florida of The Atlantic, having both analyzed data provided by the Centers for Disease Control from 2006-2008, came to similar conclusions when looking at the impact of inner cities on gun deaths.
The Chronic Disease Prevention and Control Research Center will focus on asthma, where rates are much higher among inner-city children, particularly blacks.
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