Incumbent treatment technologies in the U.S., like coagulation and flocculation, date back to the 19th century.

FORBES: Magazine Article

That damaged the surrounding tissue enough to activate the coagulation system.

ECONOMIST: Monitor

"There is reason to wonder how the use of an obscure recombinant coagulation factor marketed exclusively to hematologists came to be used so widely by cardiac surgeons, neurologists and trauma specialists, " they said.

WSJ: Hemophilia Drug's Off-Label Use Is Faulted