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Over dinner Schreibershared with Adams his disdain for combinatorial chemistry, the high-speed fabrication of synthetic molecules.
FORBES: Magazine Article
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After screening dredges up a promising drug candidate, combinatorial chemistry takes a hand.
FORBES: A hail of silver bullets
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Combinatorial chemistry elaborates lead drugs (such as the one that led to Lillys antimigraine drug) into entire families of related compounds.
FORBES: A hail of silver bullets
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Whether combinatorial chemistry will have as many uses outside the realm of drugs as in it is not yet clear.
ECONOMIST: Combinatorial chemistry
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Mario Geysen, now a senior research scientist at Glaxo Wellcome, pioneered combinatorial chemistry back in 1982 when he was at the Commonwealth Serum Laboratories in Melbourne, Australia.
FORBES: A hail of silver bullets
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Villhauer took advantage of a new rapid-fire method called "combinatorial chemistry, " which allowed him to brew hundreds of compounds simultaneously instead of one at a time.
FORBES: Fat City
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Instead of making drugs, they would use the high-tech tools of gene chips, high-throughput screening, combinatorial chemistry (the rapid mixing and matching of chemicals) and bioinformatics (software that analyzes data)--to develop entirely different compounds.
FORBES: Breaking a Sweat