That happened during the 1999 Tour de France, when he tested positive for corticosteroids.

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Prior to Benlysta, FDA last approved drugs to treat lupus, Plaquenil (hydroxychloroquine) and corticosteroids, in 1955.

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It works quickly to bring on remission, especially for people who haven't responded well to corticosteroids.

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Treatment often includes inhaled corticosteroids, to reduce inflammation, and long- and short-acting beta agonists like albuterol, to relax airway muscles.

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Twenty percent or more of people with polymyalgia rheumatica will have a least one relapse when tapering off the corticosteroids.

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Why: If corticosteroids alone aren't working, an anti-leukotriene can block the chemicals that are further fueling airway swelling and spasms.

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Mr. Armstrong admitted to Ms. Winfrey that he covered up a positive test in the 1999 Tour de France for corticosteroids.

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Only the corticosteroids, such as dexamethasone, and the progestational agents, such megesterol acetate, have proven of benefit in treatment of the loss of appetite.

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Long-term, daily use of inhaled corticosteroids may slightly slow their annual growth rate, a side effect that's thought to be reversible when children stop taking the drug.

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During the 1980s and '90s, Schering-Plough refined its focus on four key therapeutic areas and integrating new technologies to achieve important pharmaceutical advances in antihistamines, corticosteroids, antibiotics, anti-infectives and antiviral products.

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While a number of studies show corticosteroids and progestational agents cause an increase in appetite and even weight gain, these studies have not shown that they improve quality of life or survival.

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Why: Inhaled corticosteroids reduce airway inflammation long-term.

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Eerily reminiscent of the raids that transformed the 1998 Tour de France into the Tour de Farce, the raids on the hotel rooms used by 20 teams discovered stimulants, anabolic steroids and corticosteroids, as well as used syringes.

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She said she was in the room when Armstrong and two other team officials came up with a plan to backdate a prescription for corticosteroids to explain a positive steroid test result during the 1999 Tour de France.

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She also said she was in the room when Armstrong and two other team officials came up with a plan to backdate a prescription for corticosteroids for a saddle sore to explain a positive steroid test result during the 1999 Tour de France.

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She told the agency she engaged in clandestine trips to pick up and drop off what she assumed were doping products, and said she was in the room when Armstrong and two other team officials came up with a plan to backdate a prescription for corticosteroids for a saddle sore to explain a positive steroid test result during the 1999 Tour de France.

CNN: October 22, 2012 -- Updated 1721 GMT (0121 HKT)