Over 26.2 miles, a litany of issues cramps, sickness, injury can derail a premier athlete's Olympic hopes.
Certainly some women suffer more than others, debilitated by heavy bleeding, painful cramps and migraines.
Half of patients may have other leg symptoms such as heaviness, fatigue and cramps.
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Some cramps are associated with overworking the muscles, dehydration or staying too long in one position.
Training camp is very rigorous and I was prone to a lot of cramps.
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Perhaps most commonly, cramps can be due to overuse of muscles that are not accustomed to exercise.
Antidiarrheal medications may help with cramps, but they may also prolong the diarrhea, the Mayo Clinic said.
Muscle cramps are most common in people over age 65, affecting more than two-thirds of that age-group.
Norovirus causes vomiting, stomach cramps, fever and diarrhoea and it is easily spread from person to person.
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People in the area at the time reported a range of health issues, including stomach cramps, rashes, and diarrhoea.
Ms Cohen said she then started to feel sick and suffer stomach cramps.
People may also have a slight fever, headache, stomach cramps and aching limbs.
Symptoms include diarrhea, fever and abdominal cramps, which typically begin within 12 to 72 hours, according to the CDC.
Most cramps last for a few seconds or minutes and don't come back.
The doctors and nurses who treat them say the babies can suffer from nausea, vomiting, severe stomach cramps and diarrhea.
Mr Babin had complained of cramps on the first day of filming on the southern Cambodian island on 22 March.
The norovirus bug - which causes vomiting, stomach cramps, fever and diarrhoea - is easily spread from person to person.
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Some strains of the bacteria can cause severe diarrhoea, abdominal cramps and fever, and can cause fatal kidney failure in children.
After treating Lewis, Brown watched on television from Houston as his patient, competing in the U.S. Olympic trials, fell prey to cramps.
Decreased oxygenation of leg muscles due to peripheral vascular disease and the pain of diabetic neuropathy can also be mistaken for cramps.
Daily stretching and muscle strengthening can be very useful in preventing cramps.
Your doctor may suggest a stretching program, certain exercises, over-the-counter or prescription pain relievers or muscle relaxants for severe or repeated cramps.
Barely five steps later both my calves seized up in excruciating cramps.
"I thought it was a bad charley horse, so I sat down to have a smoke, and the cramps went away, " he says.
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Ms Kaur is alleged to have later placed mercury amalgam in practice manager Laura Knowles's coffee, causing her to suffer stomach cramps and sickness.
Pistorius cannot get cramps in his calves because he does not have any, and so he can never be eliminated based on this criterion.
Shortly after the incident, people in the area began reporting a range of health issues, including stomach cramps, rashes, diarrhoea, mouth ulcers and aching joints.
In this year's U.S. Olympic trials, Dathan Ritzenhein, the two-time Olympian and 5k American record holder, was eliminated from the marathon team because of leg cramps.
Serbia, beaten in last year's final, received a lifeline when Slovakia's Dominika Cibulkova retired due to severe cramps when leading 6-4 5-4 against Vesna Dolonc in Nis.
This editor did experience cartilage cramps near the backs of his ears after an hour or so of wearing the cans, however -- a niggle at best.
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