Late last week, Millennium Pharmaceuticals (nasdaq: MLNM - news - people ) disclosed in a regulatory filing that MLN-02, a treatment for Crohn's disease, was effective in a mid-stage clinical trial.
The researchers, all 256 of them, looked at seven diseases: bipolar disorder, coronary-artery disease, Crohn's disease (an inflammation of the gut), hypertension, rheumatoid arthritis, type I diabetes (the sort that develops early in life) and type II diabetes (the sort that develops later).
In 1999 Isis' (nasdaq: ISIS - news - people ) long-awaited drug for Crohn's disease, a severe intestinal disorder, failed to outperform a sugar pill in a pivotal test with 300 patients.
Chi-Med was able to skip the early-stage trial with its Crohn's disease drug candidate because its active ingredient, the herb andrographolide, has been used in China for decades to treat respiratory infections and inflammation.
Still others were diagnosed with long-term health conditions such as Crohn's disease, psoriasis, rheumatoid arthritis and thyroid disorders.
Even the Crohn's disease drug is back on track and is now in late-stage trials.
The widest experience that most have in this area has been in the treatment of traveler's diarrhea, antibiotic-associated diarrhea and the inflammatory bowel diseases (ulcerative colitis, Crohn's disease).
Abbott Laboratories' ( ABT - news - people ) Humira, for rheumatoid arthritis, psoriasis and Crohn's disease, has been one of the pharmaceutical industry's biggest success stories.
The company announced that its first stem cell product to enter clinical trials, PDA-001, recently showed very early and very dramatic results in a few Crohn's disease patients.
There are other Alzheimer's drugs in the pipeline, for instance, as well as a treatment for multiple sclerosis and Crohn's disease, Antegren, that is being developed with Biogen (nasdaq: BGEN - news - people ).
And there are other promising Alzheimer's drugs in the pipeline as well as a treatment for multiple sclerosis and Crohn's disease, called Antegren, that is being developed with Biogen (nasdaq: BGEN - news - people).
But a medicine for Crohn's disease and two lung cancer drugs, developed separately with Eli Lilly (nyse: LLY - news - people ) and Novartis (nyse: NVS - news - people ), flamed out.
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