Bad cholesterol levels were reduced by 50 percent and hs-CRP levels dropped 37 percent.
CNN: Study: Cholesterol drugs could help those with healthy levels
He picked CRP because it was the easiest measure to use to test for inflammation.
By 2001, Ridker had presented analyses of CRP's importance from completed studies of statins.
Based mostly on his work, CRP was added to guidelines as a tiebreaker test.
Crestor slashed their LDL levels to 54 and also reduced their CRP levels by 37%.
Its lead author, John Danesh of the University of Cambridge, says CRP wasn't ready for prime time.
But their cardiac risk was increased because their CRP levels were elevated (above 2 milligrams per liter).
More than 100 hours were served by CKI members and fellow high school volunteers for the CRP.
Nonetheless, having the most money won't necessarily propel a candidate to victory, says Sheila Krumholtz, CRP's executive director.
Apart from hs-CRP, scientists are looking at mouth bacteria as another possible link between gum disease and heart disease.
Exercise, and a reduction in fat, particularly around the middle, is one of the most powerful factors for lowering CRP.
Ridker planned all along to look at CRP from patients in the trial and see if it made a difference.
Recent studies have shown that the statins commonly prescribed for lowering cholesterol may also be effective for lowering CRP levels.
When combined with Zocor in Vytorin, Zetia does lower C-reactive protein (CRP), which doctors use to try and measure artery inflammation.
The child was revived with CRP and taken to a nearby hospital.
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The other day, he says, he was looking at a field that a farmer had enrolled in the Conservation Reserve Program, or CRP.
The experiment was designed to test whether people who had normal levels of bad cholesterol but high CRP could be helped by statin therapy.
Alan Tall, who wrote an editorial in the Journal saying CRP may need to be reassessed, says that even the newest data shows an effect.
"It does suggest that the CRP story was overdone, " he says.
Those with good cholesterol levels typically don't have their hs-CRP levels tested because there are no clear guidelines on who should be tested and how often.
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However, if you have other indicators for inflammation, such as elevated levels of C-reactive proteines or CRP, it might be worth discussing the possibility with your doctor.
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According to the Center for Responsive Politics (CRP), a group that tracks special-interest spending, more than 476 organizations lobbied on Capitol Hill for agriculture issues in 2006.
"It's splendid news, and that's sort of what they were waiting for to decide where CRP fit, " says Roger Blumenthal, who directs preventative cardiology at Johns Hopkins University.
And he says imaging studies like ENHANCE have not been proven to be any more meaningful that reductions in LDL or C-reactive protein (CRP), a marker of inflammation.
Adding to the debate is a new study, published this week in The Lancet, that calls into question the strength of the connection between CRP and heart disease.
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More important, Crestor cut bad cholesterol 60% and lowered CRP.
Weighing the proof that high CRP is a risk factor for heart disease that should be treated will have to wait until the study's results are analyzed and presented.
That would put the firm among the top 10 biggest spenders on lobbying in 2007--among the ranks of General Motors, Freddie Mac and Boeing--according to CRP's most recent lobbying analysis.
But that bump came at a cost: increases in cortisol, a stress hormone, and a measure of inflammation called CRP, which can raise the risk of developing heart disease and diabetes.
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