Most of Pfizer's big sellers are aging, with many losing patent protection, causing sales to crumble.
So, why did we spend 2008 watching the roads we built in 1955 crumble?
Genetic Technologies' detractors say its patents could crumble under attack from a good defense lawyer.
It looked as though Thunder might crumble as Stokes' side poured on the pressure.
Le crumble is a trendy addition to the dessert menu in even rural France.
People who crumble under the pressure of a vacation may exhibit that same behavior at home.
Transfer to paper towels to drain and cool, then remove the casings and crumble the meat.
But support for this idea began to crumble almost as soon as it became public.
The Democratic Renewal Party, which had brought the censure motion, saw its vote crumble.
Confidentiality equalled crisis and, live on television, we watched the deal crumble before our eyes.
BBC: NEWS | UK | Northern Ireland | Analysis: Why deal stalled
Vital clues about what caused the bridge to crumble may be lying in the Mississippi River.
Now the barriers they had sought to erect between philosophy and science began to crumble.
Money was raised to replace Mr Fielding's old sandstone grave memorial after it started to crumble away.
Embassytown, that outpost of the colonial power of Bremen, is starting to crumble under its own weight.
The menu includes school staples like pasta, baked potatoes, roast dinners, fish and chips and apple crumble.
Religious tolerance began to crumble, culminating seven years later in the outbreak of the 30 Years War.
It would have been easy for Wales, short on confidence and experience, to crumble after the early setback.
Yet more recently the edifice appears to have begun to erode, and in some cases, could well crumble.
He said he was "freezing" and worried the snow would crumble beneath him.
Attorneys for wineries challenging the laws are confident enough to predict direct-shipping laws nationwide will crumble within six years.
Build too weighty a project on those fragile foundations and it will crumble.
Stock valuations will crumble once the Fed abandons its easy-money policy, they say.
And Cellerant's claims of better medicine through purity may crumble under closer inspection.
They are far duller folk than their caricatures and the offences they are accused of crumble on closer examination.
If you dropped it, it would crumble flat but regain its shape flawlessly the moment you picked it up.
Some crumble under that pressure, but Alonso seems to be thriving on it.
Oh, I know I'm going to crumble and I'm trying to stay humble but I never think before I sing.
Pepsi President John Sculley, whom Jobs had picked as a mentor, ousted him in 1985--and the company began to crumble.
During the year, we saw some of the main pillars of 20th century management starting to crumble and even collapse.
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Ms. WHOOPI GOLDBERG: (As Celie) I told you, until you do right by me, everything you think about is gonna crumble.
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