Prusiner proved that prions are a deformed version of an otherwise harmless protein called PRP.
Usually patients have less serious mutations: a single front tooth or a slightly deformed face.
Treated as an outcast because of his deformed face, he was depressed and humiliated, he says.
As the weakening heart tries to pump harder, the muscle gets bigger, but becomes deformed.
After a few seconds, he noticed that some of the faces began to appear highly deformed and grotesque.
FORBES: Optical Illusion of the Day: Celebrities Become Monsters Right Before Your Eyes
As a telescope moves, its mirrors are deformed by gravity while at the same time being shaken by wind.
FORBES: European Southern Observatory (ESO) Sets 'First Light' For World's Largest Telescope
It was Irmak, who couldn't speak from his frostbitten face, but he looked at Ben Yehuda and his deformed hand.
The chassis itself was so deformed we had to cut through the faux-leather of the case to get it out.
ENGADGET: VestGuard UK Ballistic iPad Panel test: can this slate stop a bullet or two? (video)
Two sick puppies - one suffering from mange and the other with deformed legs - have been found dumped in Berkshire.
Data from the Japanese Alos spacecraft has been used to map the way the ground deformed during the most recent quake.
Of the 25 human remains, 13 had deformed skulls and five had mutilated teeth (where they are filed into shapes).
ENGADGET: Alt-week 12.22.12: strange skulls, solar portraits and 17-minute code cracking
In its support notes to users, Apple says battery packs which are "visibly deformed" are among the symptoms of battery problems.
Now 28, Riggs says he's still haunted by the story of a gentle, intelligent and yet monstrously deformed man shunned by society.
Chris then criticized Daisey for misappropriating the story of a man whose hand was deformed as a result of an industrial accident.
Richard III was portrayed as deformed by some Tudor historians and indeed the skeleton's spine is badly curved, a condition known as scoliosis.
The first sign is often when livestock give birth to deformed or dead young - which can be months after the infection has occurred.
Farmers in Devon and Cornwall say they want more information about a disease that can lead to lambs and calves being stillborn or deformed.
Schneider scrunches up his nose, a large oyster that has another smaller and deformed relative attached to its curved upper shell has caught his attention.
The silk floss for the yarn in Yuki-tsumugi weaving is produced from empty or deformed silkworm cocoons, otherwise unusable for the production of silk yarn.
The virus causes lambs and calves to be stillborn or deformed.
"We had rescued hens whose beaks had re-grown, but they were deformed like scissors - where the top beak grows off to one side, " she said.
The bees were infected with just about every bee virus known, including deformed-wing virus, sac-brood virus, and black-queen-cell virus, and also by various fungi and bacteria.
Joe have mutated into teams of fighters who travel across galaxies and time, armed to the canines with light sabres and lasers, fighting horribly deformed foes.
She is showing a series of self-portrait photographs in which she explores questions of normality and beauty in a society which, she says, considers her deformed.
Address scarcity contributes to be a strange attractor that deformed the logic of the Internet at scale and helped guarantee the cloud would become the primary architecture.
FORBES: The Link Between Scarce IP Addresses and the Centralization of the Internet
Even if a barrel is deformed after firing, Defense Distributed has designed the Liberator to use removable barrels that can be swapped in and out in seconds.
FORBES: Meet The 'Liberator': Test-Firing The World's First Fully 3D-Printed Gun
And they went to an orphanage where normal children had been confined to cribs for so long without being attended to that their bodies had become deformed.
While the backgrounds look awesome, lush, colorful, and hyper-detailed, the characters tend to have a low polygon count, and faces look pretty hideously deformed when viewed close-up.
Scientists had long assumed that these disorders must be caused by a virus, but Prusiner had proposed back in 1982 that deformed proteins, called prions, were the culprit.
As patients age, genetic mutations or unknown environmental factors may boost the production of deformed proteins, or old brain cells simply may become less able to dispose of debris.
应用推荐