It's derived from dimethylsulfoxide(DMSO), which was promoted as a pain reliever in the 1960s and 1970s until scientists discovered in animal tests that it caused eye damage in high doses.
In bladder instillation, the prescription medication dimethylsulfoxide, or DMSO, (Rimso-50) is placed into your bladder through a thin, flexible tube (catheter) inserted through the urethra.