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To date, no drug has been approved in its leaf form because plants contain a complex composition of compounds with uncertain pharmacologies, metabolisms, side-effect profiles, toxicologies, drug interactions, and no control of relative concentrations.
ECONOMIST: Egypt's challenge
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Drugstores, both the mail-order and walk-in kind, use software that warns patients of drug interactions.
FORBES: Script doctor
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The problem for regulators, though, is that interactions between drug company sales representatives and doctors occur behind closed doors--and just because a doctor is prescribing a medicine for an unapproved use doesn't mean the drug firm suggested that he do so.
FORBES: When Doctors Go Off-Label
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Girl Scout Troop develops non-pharmaceutical remedy for sleeplessness in senior citizens: When faced with the challenge of alleviating insomnia without complicated drug interactions, The Atomic Flying Pickles, a FIRST Lego League team of 6th grade Girl Scouts hailing from Los Alamos, New Mexico , came up with a novel idea.
WHITEHOUSE: The White House