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Other opioid drugs are available that are already the active form of the drug and are less influenced by this quirk in drug metabolism.
FORBES: Why Codeine is Dangerous in Some Kids After Tonsillectomy
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We usually think of drug metabolism as breaking drugs down.
FORBES: Why Codeine is Dangerous in Some Kids After Tonsillectomy
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No adverse effects from the drug's metabolism were observed.
BBC: NEWS | South Asia | Tiger collaring project suspended
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When injected in mice, the drug worked by increasing metabolism, not by suppressing appetite.
CNN: STORY HIGHLIGHTS
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Dr%20Geetha%20Srinivasan The aim of this research is to produce an advanced method of drug delivery directly to the site of infection, eliminating the conventional route of drug administration orally in which the drug often loses efficacy before it reaches the site of infection due to metabolism in the gastro-intestinal track.
UNESCO: 2012 UK and Ireland Fellows
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Dr Geetha SrinivasanThe aim of this research is to produce an advanced method of drug delivery directly to the site of infection, eliminating the conventional route of drug administration orally in which the drug often loses efficacy before it reaches the site of infection due to metabolism in the gastro-intestinal track.
UNESCO: 2012 UK and Ireland Winners
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Nanoscale materials are being used to address current drug delivery shortcomings, including water solubility, ADME (absorption, distribution, metabolism, and excretion) and toxicity.
FORBES: On the Ground Floor of Nanotechnology
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There's a drug that has been used to treat alcoholism called Antabuse, and what Antabuse does it changes the metabolism of alcohol so that people who drink and take Antabuse feel horribly, horribly sick.
NPR: Slate's Medical Examiner: Xenical OTC