At this point, McCain may need to remind the larger general election electorate of the maverick senator who more than once has been willing to break with the Republican establishment on issues such as taxes, global warming, campaign finance, immigration, torture and the execution of the war.
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The winner of the election would serve the remainder of a senator's unexpired term.
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Instead of running back to academia, Warren went on to challenge Scott, who had been the surprise winner of the 2010 election to replace the late Senator Ted Kennedy, riding into office on the strength of a telegenic pick-up truck, and the support of the suddenly powerful Tea Party.
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Kennedy's interest in the seat could mean the continuation of a family legacy in the Senate that began 56 years ago with the election of her father as the then-junior senator from Massachusetts.
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One of the most important results on Tuesday was the election of Elizabeth Warren as United States senator from Massachusetts.
He resumed his life of public service as an Ohio State senator before winning election to the House of Representatives in 1996, where he currently sits.
The libertarian senator has challenged Republicans to confront the results of the 2012 election, saying it requires outreach to new voters and a willingness to reform government.
But I think in the general election, the fact that Senator Clinton came late to the party, as it were, in terms of opposition to Iraq, to the Iraq war, she probably would not be much different from the Republican candidate, whomever that is, in terms of coming late to the party.
John Kerry surging to the front of the Democratic pack, the head of President Bush's re-election effort took aim at him Friday, charging that the Massachusetts senator's voting record shows a weakness on national security issues.
And I note, as I have in the past, that he hopes and believes that there will be at some point a return to the kind of bipartisan support for comprehensive immigration reform that we used to have in this country, led by his predecessor as President, Republican George W. Bush, and the Republican nominee for President in the last election, John McCain, Senator of Arizona.
"This is just a completely unworkable, inhumane, unthinkable proposition, to dump children on a remote island for decades to come simply because the government of the day wants to look tough on refugees in order to win the next election, " argued the Greens' Senator Sarah Hanson Young.
McCain campaigned for Bush's re-election in 2004, and the Arizona senator has become one of the strongest advocates for the war in Iraq, the thing that is most likely to define President Bush's legacy.
Blitzer interviewed all of the major candidates at some point during the 2008 presidential election cycle, including then-Senator Barack Obama and Senator John McCain.
"There is a block on the Supreme Court, that I think would be confirmed if we are not successful in this election with Vice President Gore and Senator Lieberman, who want to drastically restrict the ability of the federal government to protect and promote the civil rights and human rights and basic needs of the American people, " Clinton said.
This could hurt the state's junior (Republican) senator, Spencer Abraham, who faces one of the toughest re-election races in the country, strengthen the Democrats' position in the state legislature and even send Michigan's 18 electoral college votes to Al Gore, a determined opponent of vouchers.
Kennedy was a high-profile supporter of his fellow Massachusetts senator, John Kerry, whom Bush defeated in the November presidential election.
But it was McCain's attack on Senator Obama, it seemed to me, that signaled the start of a general election theme here.
In the first of two commentaries on Haiti, former Democratic Senator Bob Graham of Florida says the United States must help restore order before the election.
And end of term makes a nice departure point for a senator to launch a presidential bid, provided an election is on the horizon.
President Bush's re-election campaign said the senator is trying to "talk down" an economic rebound that has resulted in the creation of 1.4 million jobs since August.
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