Even when no stigma attaches to the drugs involved, most clinical trials end in failure.
Its cost position is so strong that its competitors' attempts to match it on "everyday low prices" end in failure.
Contrary to Enoch Powell's gloomy crack that all political careers end in failure, Mr Robert's main contention is that Salisbury's was crowned with success.
Worse was to come, though, so much worse indeed that Mr Weinberger's case may be said to support the dictum that all political careers end in failure.
Without her bladder functioning properly, she could get urinary sepsis that could damage the organs and end in renal failure.
Brilliant strategies, badly timed and executed, end up in failure.
Outspoken analyst and fund manager Tom Brown, of New York-based Second Curve Capital, wrote in a letter to Citigroup's board last week that "the growth strategy lately being articulated by management will end in costly failure, " and he repeated his call for a break-up of the company.
Another woman, in her eighties, with end-stage respiratory and kidney failure, had been in the unit for two weeks.
In the end, though, the real commercial victims of the failure of structural reform in Europe are not the region's existing companies, but those that are never born.
Furthermore, any failure to end the conflict in Darfur could have dire consequences for a longer-running war in southern Sudan and for another in neighbouring Uganda.
In the end, though Zune was a failure for Microsoft, Johnson said it was a worthwhile learning experience for the company.
An immediate, first-weekend failure would not be the end for Research In Motion.
FORBES: Will BlackBerry 10 Provide a 'Steve Jobs Moment' for Research In Motion's CEO?
In the end it was fear of being judged a moral failure that drove the decision.
BBC: Gaddafi killed: A new kind of US foreign policy success
Epogen's main use is to treat anemia in patients with kidney failure, also known as end-stage renal disease.
More typical was an almost eighty-year-old woman at the end of her life, with irreversible congestive heart failure, who was in the I.
The death of Morrison, who died of heart failure in a bath in Paris, effectively spelled the end for the band, although Chicago-born Manzarek took on singing duty.
The hi-tech system was introduced with one main purpose - to eliminate the possibility of vote-rigging, and give the Kenyan electorate faith in the count - but our correspondent says the failure could end up having the opposite effect.
And Raikkonen took the final point in eighth place despite retiring with engine failure five laps from the end.
BBC: SPORT | Motorsport | Formula One | Hamilton wins dramatic F1 opener
Wilberforce may have thought that God was punishing him for his failure to end the slave trade: his shame is right there in his gut.
The failure of his elections policy convinced Bush to end his support for elections in his last two years in office.
In the end she stumbled over another tax peccadillo that has haunted many politicians: failure to pay taxes for a nanny and a chauffeur.
ECONOMIST: Tom Daschle: The importance of being sinless | The
In the end, I gave up and returned to Porto Alegre, embittered by the failure of my penitential trip.
Based on that research, our economists at Vanguard isolated changes in the U.S. economy that we determined were specifically due to increases in policy uncertainty, such as the debt-ceiling debacle in August 2011, the congressional supercommittee failure in November 2011, and the fiscal-cliff crisis at the end of 2012.
That, coupled with Kuznetsova's failure to take advantage of two break points in the following game, marked the effective end of her resistance.
If they fail to strike a deal, post-war Germany's second grand coalition risks going down in history as a failure, for there will be little time to put things right before the end of its term.
ECONOMIST: Doubts are growing about Angela Merkel, at least at home
应用推荐