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The mutation freezes a crucial protein called epidermal growth factor receptor in the "on" position.
FORBES: Taking Aim at Brain Cancer
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All three drugs target the epidermal growth factor receptor (EGFR), a protein that is over-expressed in cancer cells.
FORBES: Magazine Article
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Drugs like Iressa target a protein called the epidermal growth factor receptor (EGFR), which tells cells when to divide.
FORBES: Why Cancer Drugs Need Genetic Testing
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The molecule - epidermal growth factor receptor (EGFR) - relays instructions to cells to grow and divide, and to ignore signals telling them to die.
BBC: NEWS | Health | Smart drug for lung cancer tested
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Lapatinib, it turns out, also inhibits the activity of a protein called the epidermal growth factor receptor, which has been found to be important for stem-cell proliferation.
ECONOMIST: Cancer therapy
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The public has mostly focused on Erbitux's ability to slow tumor growth by blocking epidermal growth factor receptor, a key growth-promoting protein that is overabundant in many cancer cells.
FORBES: Bristol, ImClone File On Erbitux
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Both pills inhibit a receptor for a protein called the epidermal growth factor (EGF) that many tumors seem to depend upon to grow.
FORBES: Magazine Article