Eugenol (4-allyl-2-methoxyphenol) is a fragrant compound that is commonly contained in various sorts of plants, especially in spices and medicinal herbs.

FORBES: The Lessons Of Failure: What We Can Learn From Bapineuzumab's Blowup

Furthermore, eugenol inhibits monoamine oxidase A (MAO-A) and may restore monoamines that are decreased in the brain of patients with depression.

FORBES: The Lessons Of Failure: What We Can Learn From Bapineuzumab's Blowup

This article reviews the previous investigations concerning effects of eugenol including its analogs on the CNS and describes perspectives of this highly potential compound.

FORBES: The Lessons Of Failure: What We Can Learn From Bapineuzumab's Blowup

Eugenol, like other antidepressants, increases expression of brain-derived neurotrophic factor (BDNF) gene in the hippocampus, which is necessary for an antidepressant to exhibit its activity.

FORBES: The Lessons Of Failure: What We Can Learn From Bapineuzumab's Blowup

Thus, eugenol can be a good medicine for AD and depression.

FORBES: The Lessons Of Failure: What We Can Learn From Bapineuzumab's Blowup

Like a cocktail expert, I would press my herbs into sugar syrup to capture the fragrance of their volatile oils linalool, eugenol, citral, thujone, camphor.

NPR: Garden in a Glass: Herbal Teas, Lavender Martinis

Besides, anti-inflammatory and antioxidative activities of eugenol are known.

FORBES: The Lessons Of Failure: What We Can Learn From Bapineuzumab's Blowup

Moreover, eugenol possesses an antidepressant-like activity.

FORBES: The Lessons Of Failure: What We Can Learn From Bapineuzumab's Blowup

Eugenol, a methoxyphenol found in various essential oils such as clove, bay laurel, cinnamon leaf, and rosemary, appears to be a particulary effective peorxynitrites scavenger (the methyl group binds to peroxynitrites and the phenol group converts it into water and a nitrogen dioxide anion).

FORBES: The Lessons Of Failure: What We Can Learn From Bapineuzumab's Blowup