In the late 19th Century, a doctor experimented with grinding peanuts in a hand-operated meat grinder.

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Engineers designed the dies on paper, and skilled craftsmen used hand-operated machinery to cut the die from a hunk of steel.

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In the final seconds, Pan pulled a hand-operated emergency brake.

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The doctors and nurses at his hospital, working heroically, moved 215 patients, including infants on ventilators whose lungs were kept working with hand-operated plastic bags, to other hospitals like Mount Sinai Medical Center four miles north.

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