As anyone who has endured heartburn knows, it has nothing to do with the heart--but the burn part is very real.

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When a drug is likely to cause a severe side effect--say, an increased risk of heart attack, an allergic reaction that causes the skin to burn or liver failure--the standard practice is to warn patients and doctors about the product's labeling, and to send out warning letters to physicians who might prescribe the medicine.

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The 400PT is a heavy monster that won't slide around the floor and it has cutting-edge electronics that measure heart rate, calorie burn and power output by the watt.

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They make record time in a fleet of small cars, ambu-cycles, ambu-tractors and ambu-boats -- all equipped with heart defibrillators, breathing tubes, burn wraps and maternity kits.

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But sadly, as your heart rate rises and that familiar burn permeates your muscles, the self-assurance you seek remains elusive, replaced instead by a silent war that wages within your brain.

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