They were given this tremendous overdose of heparin at the hospital because of a labeling mix-up.
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The anti-coagulants warfarin and heparin can be easily reversed if a patient develops major bleeding.
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Coumadin takes weeks to start having an effect, but Exanta begins working in two hours, like heparin.
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"Almost all forms of heart surgery require heparin, " says Mark Stafford-Smith, a cardiothoracic anesthesiologist at Duke University.
But cardiologists haven't given up on old-fashioned heparin, which is often used in combination with other anti-clotting drugs.
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Improvements on the Horizon: Heparin has been around for about 70 years.
's (nasdaq: MDCO - news - people ) Angiomax, which appeared to be as effective as heparin but safer in a recent clinical trial.
Neutralase, an enzyme that chews up heparin, could replace protamine.
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