They are critical for priming the newborn's immune system to learn which agents are potentially dangerous and which, particularly those on foods, can be given a pass.

CNN: Connection between dirty diapers, childhood health

TLRs tend to prompt the immune system to respond to infectious agents like bacteria and viruses - not allergens.

BBC: Immune system 'fights allergies'

Many patients fail to respond to currently available therapies, and some of the drugs currently used to treat moderate to severe IBD, including steroids and other immune modulatory agents, can be toxic to the human system.

BBC: News | Health | Bowel disease drug breakthrough