The first human trial is slated for early next year, in patients with so-called complete injuries.
Both studies were done in patients with serious heart disease, who may differ from other patients.
Similarly, Erivedge targets cancers in patients with mutations in a specific gene known as PTCH1.
The letter will inform physicians that Pradaxa is now contraindicated in patients with mechanical heart valves.
FORBES: Pradaxa To Be Contraindicated In Patients With Mechanical Heart Valves
In 2009, Bolli was ready to launch the SCIPIO trial (Cardiac Stem Cells in Patients with Cardiomyopathy).
The drug was being tested in patients with stage 4 chronic kidney disease and type 2 diabetes.
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Amgen has published a big study showing that its Vectibix only works in patients with normal kras.
If this could be proven in patients with cardiovascular disease, one could envision a variety of benefits.
Dronedarone should not be used in patients with permanent AF, heart failure, or left ventricular systolic dysfunction.
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By contrast, Roche recently doubled the size of a trial testing a compound in patients with early-stage disease.
What limits the revenue potential of the drug is its lower efficacy in patients with impaired kidney functions.
Epogen's main use is to treat anemia in patients with kidney failure, also known as end-stage renal disease.
Then she asked a series of questions, targeting issues that tend to arise in patients with terminal illness.
The FDA recently rejected the an indication for the use of rivaroxaban in patients with acute coronary syndrome.
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TOBI, a version of the antibiotic tobramycin, designed to treat fatal lung infections in patients with cystic fibrosis.
It says it is using the latest world-class diagnostic tests to look for the disease in patients with symptoms.
The country is seeing a 6% annual increase in patients with renal failure (caused mostly by diabetes and obesity).
This scale measures behavioral problems seen in patients with psychiatric and neurological disorders, including delusions, hallucinations, agitation, and anxiety.
Later that year, a second study in patients with a heart valve problem also failed to show a benefit.
Genentech is testing a derivative of Avastin, rhuFab V2, in patients with macular degeneration, a leading cause of blindness.
But it says Bydureon shouldn't be used in patients with a personal or family history of medullary thyroid carcinoma.
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Another, called SHARP, compares Vytorin, Zocor and placebo in patients with kidney disease.
The safety and effectiveness of KYNAMRO have not been established in patients with hypercholesterolemia who do not have HoFH.
FORBES: FDA Approves Mipomersen For Homozygous Familial Hypercholesterolemia
The safety and effectiveness of JUXTAPID have not been established in patients with hypercholesterolemia who do not have HoFH.
FORBES: FDA Approves Lomitapide For Homozygous Familial Hypercholesterolemia
's clinical trial of a gene therapy in patients with advanced heart failure.
The trials include two in patients with APOE4 (an Alzheimer's disease risk factor) and two in patients without the gene.
The Symplicity HTN-2 trial is an international, multi-center, prospective, randomized, controlled study of renal denervation in patients with treatment-resistant hypertension.
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Pfizer says the problems only appeared in patients with a very high risk of heart disease who were undergoing surgery.
"Overall, I'm very pleased with the fact that intense cholesterol lowering reduces coronary events in patients with aortic stenosis, " said Braunwald.
Overall there has been a 30% or 40%, increase in patients with the main pressures at evenings and weekends, he added.
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