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The drug works because its molecular structure matches receptors on the toxin, locking them together and inactivating the poison.
BBC: Fish food poisoning breakthrough
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Xolair is a monoclonal antibody to IgE that works like a Star Wars missile defense for allergies, binding to and inactivating excess IgE before it can trigger an attack.
FORBES: Magazine Article
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Peroxynitrites contribute to the hyperphosphorylation of tau proteins by oxidating g-protein coupled receptors and trysoine kinase receptors preventing protein kinase C and AKT from inactivating the enzyme GSK3 which is necessary to prevent the hyperphosphorylation of tau proteins.
FORBES: The Lessons Of Failure: What We Can Learn From Bapineuzumab's Blowup
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It is believed that their strong electric charges attract them either to the viruses (thus inactivating them) or to the cells of the vaginal wall (thus covering those cells like a coat of paint and preventing viruses from entering the body).
ECONOMIST: HIV microbicides