Redknapp sent on O'Hara for the ineffective Bentley at half-time - and the change had an instant and dramatic impact.

BBC: Tottenham 4-1 Burnley

In the world of agriculture, as with popular medicine, the theory is to treat the symptom (in this case insect invasions) and to hope that by the time fix becomes ineffective we have something else figured out to spray, engineer or swallow to re-bandaid the problem.

FORBES: Genetic Engineering: A Food Fix?

Ancelotti used half-time to replace the ineffective John Mikel Obi with first-choice holding midfielder Michael Essien and the move seemed to give Chelsea added impetus.

BBC: Chelsea 1-1 Everton (aet)

Desperate to see his side convert their dominance into goals, Brown replaced the ineffective Garcia with Nicky Barmby shortly after half-time and Hull immediately began playing with a greater sense of urgency and belief.

BBC: Hull 2-1 Stoke

Ineffective opportunity management eventually leads to loss of money, time, and positioning with customers who are (or should be) core customers.

FORBES: How to Break Through a Growth Stall

Fitzgerald believes that standard inpatient treatment for a set period of time, or until an addict is "cured, " is ineffective.

FORBES: The Most Expensive Addictions