This was because by this stage, the immune system had destroyed the body's islet cells.
Islet cell cancer tends to spread to the surrounding lymph nodes, stomach, small intestine and liver.
Also, there are many more potential donors than with islet cells from the deceased.
BBC: Many people with diabetes must have regular insulin shots
Usually, this is the result of an immune reaction that destroys the islet cells.
The soft pink sands and islet here are undeniably enticing and, except for in high summer, serene.
One trial aims to cure diabetes by transplanting insulin-producing islet cells from deceased donors into diabetic patients.
The procedure, known as pancreatic islet transplantation, involves injections of healthy islets, or cell clusters, that release insulin.
When malignant, islet cell cancers do not generally respond well to chemotherapy, and the treatment is mainly palliative.
Islet cells, found in the pancreas, could theoretically be developed from stem cells.
But Jobs suffered from a rarer and less fatal form of the disease, called islet cell pancreatic cancer.
The shifts, on the isolated islet of the Calf of Man, run for about a week at a time.
BBC: Calf of Man islet rat-cull project calls for volunteers
Tombolo: accretionary deposit of sand or gravel joining a small islet or rock to a larger island or landmass.
Moreover, Novartis is already testing its drug in other diseases including islet cell carcinoma, a cancer of the insulin-producing cells.
Your type I or juvenile-onset diabetes is due to the islet cells located in your pancreas no longer producing insulin.
Once these cells, called islet cells, are destroyed by the immune system, the body has no way of making insulin.
It is a rare type of cancer called pancreatic neuroendocrine tumor that afflicts the hormone producing islet cells in the pancreas.
Manx National Heritage (MNH) has been carrying out a rat cull on the islet to remove the threat from the birds.
In summer the cave can get seriously crowded, so you may want to head to the less-visited Green Grotto on the nearby islet of Ravnik.
WSJ: Island-Hopping in Sweden, the BVIs, Washington State and Croatia
Two or more whole pancreases from dead donors are needed for an islet transplantation, compared to just half of a living pancreas, experts have found.
BBC: Many people with diabetes must have regular insulin shots
Early increased growth is associated with the body making more insulin, which is thought to increase the likelihood of an autoimmune response to pancreatic islet cells.
The new transplant technique is "extremely" gentle on delicate islet cells, causing little or none of the cellular fragmentation that occurs during hepatic portal injection, they said.
Three days later the Kon-Tiki struck a reef and the crew was beached on an uninhabited islet of Raroia Island -- 101 days and 4, 338 miles from Peru.
Islet stem cells currently are obtained from human organ donors.
Two injection sites were used: the surface of the small intestine and the hepatic portal vein that connects the pancreas and the liver, where islet transplantation normally is performed.
Many Caribbean countries object, too, to Venezuela's claim to the islet of Aves some 300 miles (480 kms) north of its coast, which hugely expands its claims for fishing grounds.
Patients who retain even a minor amount of natural insulin production are far less likely to go blind or fall into a coma from insulin overdosage than those who lose all their islet cells.
Now into this gloom comes a new type of drug, called an anti-CD3 antibody, that aims for the first time to delay or prevent development of the devastating disease by arresting the immune system's attack on pancreatic islet cells.
Every species on the island retreated to a small islet offshore, Boatswainbird Island, except for a few individuals that held on to the most inaccessible cliffs, and the phenomenally scrappy wide-awake terns that visit the southern plains to breed.
Among them are neural cells to treat spinal cord injury and degenerative nervous system diseases, cardiomyocytes to treat heart disease, pancreatic islet cells to treat diabetes, dendritic cells for cancer therapy, chondrocytes for arthritis, osteoblasts to rebuild bone and hepatocytes for drug discovery and liver failure.
应用推荐