Nasa's new Space Launch System (SLS) is a multi-billion-dollar venture to take humans beyond the International SpaceStation (ISS) and the confines of low-Earth orbit.
Following the retirement of the US space shuttle in 2011, the only way to transfer astronauts to the International SpaceStation (ISS) is aboard the three-seat Russian Soyuz vehicle.
Passengers will ride the rocket plane for the fun of it, but scientists would use it for the same reasons they also fly experiments on the International SpaceStation (ISS) or on sounding rockets - to access microgravity conditions.
Dr Patrick's first mission was as the robotic arm operator on STS-116 - a mission of the Discovery shuttle in 2006 to continue the construction of the International SpaceStation (ISS).
Lift-off from the Kourou spaceport occurred at 18 hours, 50 minutes and 55 seconds local time (2150.55 GMT) - the instant needed to put the truck on the right path to catch the International SpaceStation (ISS) on Thursday next week.