What I would also say is that we recognize that our strategy comes with it a certain amount of complexity, lengthiness, and unpredictability, because we are seeking innovative medically important therapies.
But there are certain points to which it is essential that we should all now commit ourselves as publicly as we can, while our visions are still unclouded.
"Given what we see, it is certain that a criminal line of inquiry is to be number one, " said the prosecutor.
All that we know for certain is that Stuxnet is a weapon and it is currently being used to wage a battle.
It is not certain whether we have recognized the fact that the Bolivarian Alliance and their allies aspire to weaken and eventually defeat their American neighbor to the North.
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It is also the case that we have a certain amount of experience in making the hard decisions and mustering the political will to take the actions necessary to save our financial system and, in fact, the global financial system, which is what happened in 2008 and 2009.
"Now that we have looked at all the evidence and made final preparations for the court case, we remain certain that it is the right thing to do, " said Brian Lightman of the Association of School and College Leaders (ASCL).
But what it does point out is that there are certain problems with the idea that we actually had economic growth during those war years.
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"If we don't help them, it is certain that al Qaeda will take them, " he said.
It is almost certain that the new politics, whatever the Web does to the way we govern, will involve that kind of emotionally driven fellow feeling.
"The sell-off is a step into the unknown in that we cannot be certain that it would provide service equal to that provided by the RAF, " said Mr Jones.
Security there is very bad, everyone knows us and what we do and it's almost certain that if we were to go, we'd be captured by the Taliban.
We want to work with you on health reform and making certain that we do it in an affordable, cost-effective way that is going to reduce bureaucracy, reduce government interference, and reduce costs to individuals and to taxpayers.
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"Around 25% of Victorian men had syphilis and he may have had it too - we'll never know - but one thing that's almost certain is that he didn't die of it, " Mr Holland told BBC News Online.
"Already the market is delivering superfast internet speeds of 50Mbps to half the country but we cannot be certain that it will reach the communities that are not currently served, " said Business Secretary Lord Mandelson in a statement unveiling the consultation.
My prediction is that it will probably come in June but I can't absolutely be certain of that and my prediction is that I know that we can win and my prediction is that we'll now pull together and we'll do enough to win but I know certainly that we can.
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